Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?
M Kou, L Huang, J Yang, Z Chiang, S Chen, J Liu… - Cell Death & …, 2022 - nature.com
Mesenchymal stem cells (MSCs) can be widely isolated from various tissues including bone
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …
Extracellular vesicles as a next-generation drug delivery platform
Extracellular-vesicle-based cell-to-cell communication is conserved across all kingdoms of
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …
RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
Extracellular vesicles in kidney disease
C Grange, B Bussolati - Nature Reviews Nephrology, 2022 - nature.com
Extracellular vesicles are released by the majority of cell types and circulate in body fluids.
They function as a long-distance cell-to-cell communication mechanism that modulates the …
They function as a long-distance cell-to-cell communication mechanism that modulates the …
Extracellular vesicles versus synthetic nanoparticles for drug delivery
Cell-released biological nanoparticles, that is, extracellular vesicles (EVs), are emerging
drug carriers with high complexity. EV-based drug delivery exploits intrinsic mechanisms for …
drug carriers with high complexity. EV-based drug delivery exploits intrinsic mechanisms for …
A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation
Nanoparticles can acquire a plasma protein corona defining their biological identity. Corona
functions were previously considered for cell‐derived extracellular vesicles (EVs). Here we …
functions were previously considered for cell‐derived extracellular vesicles (EVs). Here we …
Extracellular vesicles: mediators of intercellular communication in tissue injury and disease
G Berumen Sánchez, KE Bunn, HH Pua… - Cell Communication and …, 2021 - Springer
Intercellular communication is a critical process that ensures cooperation between distinct
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more
than 44 million people worldwide. Despite the high disease burden, there is no effective …
than 44 million people worldwide. Despite the high disease burden, there is no effective …
Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: present and future
SR Li, QW Man, X Gao, H Lin, J Wang… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐bilayer membrane structures secreted by most cell
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …
Improved MSC minimal criteria to maximize patient safety: a call to embrace tissue factor and hemocompatibility assessment of MSC products
The number of mesenchymal stromal/stem cell (MSC) therapeutics and types of clinical
applications have greatly diversified during the past decade, including rapid growth of poorly …
applications have greatly diversified during the past decade, including rapid growth of poorly …