Big data, big knowledge: big data for personalized healthcare
The idea that the purely phenomenological knowledge that we can extract by analyzing
large amounts of data can be useful in healthcare seems to contradict the desire of VPH …
large amounts of data can be useful in healthcare seems to contradict the desire of VPH …
In silico clinical trials: how computer simulation will transform the biomedical industry
The term 'in silico clinical trials indicates the use of individualised computer simulation in the
development or regulatory evaluation of a medicinal product, medical device, or medical …
development or regulatory evaluation of a medicinal product, medical device, or medical …
Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis
The surgeon general of the USA defines osteoporosis as “a skeletal disorder characterized
by compromised bone strength, predisposing to an increased risk of fracture.” Measuring …
by compromised bone strength, predisposing to an increased risk of fracture.” Measuring …
Osteoporosis and hip fracture risk from routine computed tomography scans: the fracture, osteoporosis, and CT utilization study (FOCUS)
AL Adams, H Fischer, DL Kopperdahl… - Journal of Bone and …, 2018 - academic.oup.com
Methods now exist for analyzing previously taken clinical computed tomography (CT) scans
to measure a dual‐energy X‐ray absorptiometry (DXA)‐equivalent bone mineral density …
to measure a dual‐energy X‐ray absorptiometry (DXA)‐equivalent bone mineral density …
Patient-specific finite element estimated femur strength as a predictor of the risk of hip fracture: the effect of methodological determinants
A finite element modelling pipeline was adopted to predict femur strength in a retrospective
cohort of 100 women. The effects of the imaging protocol and the meshing technique on the …
cohort of 100 women. The effects of the imaging protocol and the meshing technique on the …
Are CT-based finite element model predictions of femoral bone strengthening clinically useful?
Abstract Purpose of Review This study reviews the available literature to compare the
accuracy of areal bone mineral density derived from dual X-ray absorptiometry (DXA-aBMD) …
accuracy of areal bone mineral density derived from dual X-ray absorptiometry (DXA-aBMD) …
Fracture prediction by computed tomography and finite element analysis: current and future perspectives
Abstract Purpose of Review This review critiques the ability of CT-based methods to predict
incident hip and vertebral fractures. Recent Findings CT-based techniques with concurrent …
incident hip and vertebral fractures. Recent Findings CT-based techniques with concurrent …
A review of CT-based fracture risk assessment with finite element modeling and machine learning
Abstract Purpose of Review We reviewed advances over the past 3 years in assessment of
fracture risk based on CT scans, considering methods that use finite element models …
fracture risk based on CT scans, considering methods that use finite element models …
The virtual physiological human: ten years after
Biomedical research and clinical practice are struggling to cope with the growing complexity
that the progress of health care involves. The most challenging diseases, those with the …
that the progress of health care involves. The most challenging diseases, those with the …
Interactive graph-cut segmentation for fast creation of finite element models from clinical ct data for hip fracture prediction
Y Pauchard, T Fitze, D Browarnik… - Computer methods in …, 2016 - Taylor & Francis
In this study, we propose interactive graph cut image segmentation for fast creation of femur
finite element (FE) models from clinical computed tomography scans for hip fracture …
finite element (FE) models from clinical computed tomography scans for hip fracture …