Emerging insights into head and neck cancer metastasis

CT Allen, JH Law, GP Dunn, R Uppaluri - Head & neck, 2013 - Wiley Online Library
The purpose of this review was to provide biological concepts of head and neck cancer
metastasis. To attain this goal, we analyzed peer‐reviewed articles related to head and neck …

Molecular mechanisms of head and neck cancer

AM Deshpande, DT Wong - Expert review of anticancer therapy, 2008 - Taylor & Francis
Despite advances in understanding the underlying genetics, squamous cell carcinoma of
the head and neck (SCCHN) remains a major health risk and one of the leading causes of …

Vasculogenic mimicry contributes to lymph node metastasis of laryngeal squamous cell carcinoma

W Wang, P Lin, C Han, W Cai, X Zhao… - Journal of Experimental & …, 2010 - Springer
Background Survival of laryngeal squamous cell carcinoma (LSCC) patients has remained
unchanged over recent years due to its uncontrolled recurrence and local lymph node …

Tumor secretion of VEGF induces endothelial cells to suppress T cell functions through the production of PGE2

JK Mulligan, SA Rosenzweig… - Journal of …, 2010 - journals.lww.com
Endothelial cells are potent regulators of immune cell functions and have therefore been
examined to determine their role in tumor-induced immune suppression. Previous studies by …

[HTML][HTML] Overexpressed tryptophanyl-tRNA synthetase, an angiostatic protein, enhances oral cancer cell invasiveness

CW Lee, KP Chang, YY Chen, Y Liang, C Hsueh… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Oral squamous cell carcinoma (OSCC) is one of the most common neoplasms worldwide.
Previously, we identified the angiostatic agent tryptophanyl-tRNA synthetase (TrpRS) as a …

Immunohistochemical analysis of integrins αvβ3, αvβ5 and α5β1, and their ligands, fibrinogen, fibronectin, osteopontin and vitronectin, in frozen sections of human …

EM Fabricius, GP Wildner… - Experimental and …, 2011 - spandidos-publications.com
Integrins mediate the interaction of cells with the extracellular matrix and are believed to be
involved in tumor cell survival and metastasis, and in tumor angiogenesis. We used …

Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions

JK Mulligan, TA Day, MB Gillespie, SA Rosenzweig… - Human immunology, 2009 - Elsevier
Patients with oral squamous cell carcinoma (OSCC) have severe defects in antitumor
immune function. Endothelial cells are potential regulators of immune cell function and have …

Evaluation of lymphocyte apoptosis in patients with oral cancer

F Bin-Alee, A Arayataweegool… - Journal of Applied Oral …, 2020 - SciELO Brasil
Objectives To evaluate apoptotic levels of peripheral blood mononuclear cells (PBMCs) and
apoptotic regulatory proteins (Bax and Bcl-2) in lymphocyte subsets of oral cancer (OC) …

Vasculogenic mimicry is a key prognostic factor for laryngeal squamous cell carcinoma: a new pattern of blood supply

LIN Peng, W Wei, BC Sun, W Cai, L Li… - Chinese Medical …, 2012 - journals.lww.com
Background Recurrence and local lymph node metastasis affected the prognosis of patients
with laryngeal cancer. The aim of this study was to analyze clinical and pathological …

Genomic alteration in head and neck squamous cell carcinoma (HNSCC) cell lines inferred from karyoty**, molecular cytogenetics, and Array comparative genomic …

W Singchat, E Hitakomate, B Rerkarmnuaychoke… - PLoS …, 2016 - journals.plos.org
Genomic alteration in head and neck squamous cell carcinoma (HNSCC) was studied in two
cell line pairs (HN30-HN31 and HN4-HN12) using conventional C-banding, multiplex …