Simulation of adaptive immune receptors and repertoires with complex immune information to guide the development and benchmarking of AIRR machine learning

M Chernigovskaya, M Pavlović, C Kanduri… - Nucleic Acids …, 2025‏ - academic.oup.com
Abstract Machine learning (ML) has shown great potential in the adaptive immune receptor
repertoire (AIRR) field. However, there is a lack of large-scale ground-truth experimental …

AIRIVA: a deep generative model of adaptive immune repertoires

MF Pradier, N Prasad, P Chapfuwa… - Machine Learning …, 2023‏ - proceedings.mlr.press
Recent advances in immunomics have shown that T-cell receptor (TCR) signatures can
accurately predict active or recent infection by leveraging the high specificity of TCR binding …