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[HTML][HTML] Adult neurogenesis in the hippocampus: from stem cells to behavior
The dentate gyrus of the mammalian hippocampus continuously generates new neurons
during adulthood. These adult-born neurons become functionally active and are thought to …
during adulthood. These adult-born neurons become functionally active and are thought to …
Electrospun polymer micro/nanofibers as pharmaceutical repositories for healthcare
X Feng, J Li, X Zhang, T Liu, J Ding, X Chen - Journal of Controlled …, 2019 - Elsevier
Electrospun polymer micro/nanofibers have been widely explored as platforms for controlled
delivery of therapeutic agents. Electrospun fibers are featured by large surface area, high …
delivery of therapeutic agents. Electrospun fibers are featured by large surface area, high …
The mechanisms of Hedgehog signalling and its roles in development and disease
The cloning of the founding member of the Hedgehog (HH) family of secreted proteins two
decades ago inaugurated a field that has diversified to encompass embryonic development …
decades ago inaugurated a field that has diversified to encompass embryonic development …
Hedgehog signaling: from basic biology to cancer therapy
The Hedgehog (HH) signaling pathway was discovered originally as a key pathway in
embryonic patterning and development. Since its discovery, it has become increasingly …
embryonic patterning and development. Since its discovery, it has become increasingly …
[HTML][HTML] Neuroinflammation and neurogenesis in Alzheimer's disease and potential therapeutic approaches
In adult brain, new neurons are generated throughout adulthood in the subventricular zone
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …
Roles for Hedgehog signaling in adult organ homeostasis and repair
The hedgehog (HH) pathway is well known for its mitogenic and morphogenic functions
during development, and HH signaling continues in discrete populations of cells within …
during development, and HH signaling continues in discrete populations of cells within …
Adult neurogenesis in the mammalian central nervous system
Forty years since the initial discovery of neurogenesis in the postnatal rat hippocampus,
investigators have now firmly established that active neurogenesis from neural progenitors …
investigators have now firmly established that active neurogenesis from neural progenitors …
Wnt signalling regulates adult hippocampal neurogenesis
The generation of new neurons from neural stem cells is restricted to two regions of the adult
mammalian central nervous system: the subventricular zone of the lateral ventricle, and the …
mammalian central nervous system: the subventricular zone of the lateral ventricle, and the …
Substrate modulus directs neural stem cell behavior
Although biochemical signals that modulate stem cell self-renewal and differentiation were
extensively studied, only recently were the mechanical properties of a stem cell's …
extensively studied, only recently were the mechanical properties of a stem cell's …
Applying the principles of stem-cell biology to cancer
Why are tumours heterogeneous, in terms of cell phenotype and proliferative potential, even
in cases in which all cells are derived from a single clone? Ongoing mutagenesis can …
in cases in which all cells are derived from a single clone? Ongoing mutagenesis can …