[HTML][HTML] Therapeutic potential of snake venom: Toxin distribution and opportunities in deep learning for novel drug discovery

A Bedraoui, M Suntravat, S El Mejjad, S Enezari… - Medicine in Drug …, 2024 - Elsevier
Snake venom is a rich source of bioactive molecules that hold great promise for therapeutic
applications. These molecules can be broadly classified into enzymes and non-enzymes …

[HTML][HTML] Exploring the Diversity and Function of Serine Proteases in Toxicofera Reptile Venoms: A Comprehensive Overview

JFD Vidal, MF Schwartz, AV Garay, NF Valadares… - Toxins, 2024 - mdpi.com
Toxicofera reptile venoms are composed of several toxins, including serine proteases.
These proteases are glycosylated enzymes that affect the prey's hemostatic system. Their …

Hydrogen peroxide from l-amino acid oxidase of king cobra (Ophiophagus hannah) venom attenuates Pseudomonas biofilms

U Singkham-In, W Thaveekarn, J Noiphrom, O Khow… - Scientific Reports, 2023 - nature.com
Because of the high incidence of Pseudomonas aeruginosa biofilms-related nosocomial
infections, venoms from common Thai snakes were tested. Although venoms from king …

Higher fibrinogen and neutrophil-to-lymphocyte ratio are associated with the early poor response to intravenous thrombolysis in acute ischemic stroke

M Deng, K Song, Y Tong, S Chen, W Xu, G He… - Frontiers in …, 2024 - frontiersin.org
Background Inflammation and platelet activation play pivotal roles in acute ischemic stroke
(AIS) pathogenesis. Early response to thrombolysis is a vital indicator for the long-term …

[HTML][HTML] Emerging Trends in Snake Venom-Loaded Nanobiosystems for Advanced Medical Applications: A Comprehensive Overview

ÁEF Alves, ABC Barros, LCF Silva, LMM Carvalho… - Pharmaceutics, 2025 - mdpi.com
Advances in medical nanobiotechnology have notably enhanced the application of snake
venom toxins, facilitating the development of new therapies with animal-derived toxins. The …

Two-Dimensional Blue Native/SDS Polyacrylamide Gel Electrophoresis for Analysis of Brazilian Bothrops Snake Venoms

N Ferreira de Oliveira, ATA Sachetto, ML Santoro - Toxins, 2022 - mdpi.com
Viperidae snakes are the most important agents of snakebites in Brazil. The protein
composition of snake venoms has been frequently analyzed by means of electrophoretic …

Intensive mannitol slow infusion post‐stenting may attenuate stenting‐related early adverse effects in patients with cerebral venous sinus stenosis

G Han, S Wan, C Dandu, D Zhou… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims To analyze intensive slow mannitol poststenting on attenuating stenting‐related early
adverse effects in cerebral venous sinus stenosis (CVSS). Methods This real‐world study …

Atrase A, a P-III class metalloproteinase purified from cobra venom, exhibits potent anticoagulant activity by inhibiting coagulation pathway and activating the …

XJ Zhong, CE Wang, YN Li, QY Zhang, QY Sun - Heliyon, 2024 - cell.com
Snake venoms, comprising a complex array of protein-rich components, an important part of
which are snake venom metalloproteinases (SVMPs). These SVMPs, which are …

The BE COOL Treatments (Batroxobin, oxygEn, Conditioning, and cOOLing): Emerging Adjunct Therapies for Ischemic Cerebrovascular Disease

S Song, H Wu, X Ji, R Meng - Journal of Clinical Medicine, 2022 - mdpi.com
Ischemic cerebrovascular disease (ICD), the most common neurological disease worldwide,
can be classified based on the onset time (acute/chronic) and the type of cerebral blood …

Efficacy and safety of batroxobin in patients with acute ischemic stroke: A multicenter retrospective analysis

S Liu, S Wang, Q Zou, Y Pu, X Li, Z Hang… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims The objective of this study was to evaluate the effectiveness of batroxobin in improving
functional outcomes and reducing stroke recurrence among patients with acute ischemic …