Getting to know ovarian cancer ascites: opportunities for targeted therapy-based translational research
N Ahmed, KL Stenvers - Frontiers in oncology, 2013 - frontiersin.org
More than one third of ovarian cancer patients present with ascites at diagnosis, and almost
all have ascites at recurrence. The presence of ascites correlates with the peritoneal spread …
all have ascites at recurrence. The presence of ascites correlates with the peritoneal spread …
Meeting the challenge of ascites in ovarian cancer: new avenues for therapy and research
E Kipps, DSP Tan, SB Kaye - Nature Reviews Cancer, 2013 - nature.com
Malignant ascites presents a considerable clinical challenge to the management of ovarian
cancer, but also provides a wealth of opportunities for translational research. The …
cancer, but also provides a wealth of opportunities for translational research. The …
[PDF][PDF] Autotaxin suppresses cytotoxic T cells via LPAR5 to promote anti–PD-1 resistance in non–small cell lung cancer
JM Konen, BL Rodriguez, H Wu… - Journal of Clinical …, 2023 - Am Soc Clin Investig
Non–small cell lung cancers that harbor concurrent KRAS and TP53 (KP) mutations are
immunologically warm tumors with partial responsiveness to anti–PD-(L) 1 blockade; …
immunologically warm tumors with partial responsiveness to anti–PD-(L) 1 blockade; …
Malignant ascites in ovarian cancer: cellular, acellular, and biophysical determinants of molecular characteristics and therapy response
Simple Summary Accumulation of excess fluid in the abdomen typically indicates abnormal
function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or …
function or disease, such as cancer, in the underlying tissues. This accumulation of fluid, or …
The biology of ovarian cancer: new opportunities for translation
Over the past two decades, the 5-year survival for ovarian cancer patients has substantially
improved owing to more effective surgery and treatment with empirically optimized …
improved owing to more effective surgery and treatment with empirically optimized …
The unique molecular and cellular microenvironment of ovarian cancer
T Worzfeld, E Pogge von Strandmann, M Huber… - Frontiers in …, 2017 - frontiersin.org
The reciprocal interplay of cancer cells and host cells is an indispensable prerequisite for
tumor growth and progression. Cells of both the innate and adaptive immune system, in …
tumor growth and progression. Cells of both the innate and adaptive immune system, in …
Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8
Triple-negative breast cancers (TNBC) are aggressive with no effective targeted therapies. A
combined database analysis identified 32 inflammation-related genes differentially …
combined database analysis identified 32 inflammation-related genes differentially …
The emerging role of lysophosphatidic acid in cancer
The bioactive phospholipid lysophosphatidic acid (LPA) stimulates cell proliferation,
migration and survival by acting on its cognate G-protein-coupled receptors. Aberrant LPA …
migration and survival by acting on its cognate G-protein-coupled receptors. Aberrant LPA …
National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian …
Abstract Background: Updated National Academy of Clinical Biochemistry (NACB)
Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been …
Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been …
The role of inflammation and inflammatory mediators in the development, progression, metastasis, and chemoresistance of epithelial ovarian cancer
Inflammation plays a role in the initiation and development of many types of cancers,
including epithelial ovarian cancer (EOC) and high grade serous ovarian cancer (HGSC), a …
including epithelial ovarian cancer (EOC) and high grade serous ovarian cancer (HGSC), a …