Single-cell technologies have contributed to unravelling tumour heterogeneity, now
considered a hallmark of cancer and one of the main causes of tumour resistance to cancer …

The analysis of circulating tumor cells (CTCs) is an outstanding tool to provide insights into
the biology of metastatic cancers, to monitor disease progression and with potential for use …

Traditional immunohistochemistry (IHC) has already become an essential method of
diagnosis and therapy in cancer management. However, this antibody-based technique is …

High parameter imaging is an important tool in the life sciences for both discovery and
healthcare applications. Imaging Mass Cytometry (IMC) and Multiplexed Ion Beam Imaging …

Over the past decade, cancer diagnosis has expanded to include liquid biopsies in addition
to tissue biopsies. Liquid biopsies can result in earlier and more accurate diagnosis and …

Imaging flow cytometry (IFC) captures multichannel images of hundreds of thousands of
single cells within minutes. IFC is seeing a paradigm shift from low-to high-information …

Imaging mass cytometry (IMC) enables the in situ analysis of in-depth-phenotyped cells in
their native microenvironment within the preserved architecture of a single tissue section. To …

Cancers exhibit functional and structural diversity in distinct patients. In this mass, normal
and malignant cells create tumor microenvironment that is heterogeneous among patients. A …

The integrative analysis of tumor immune microenvironment (TiME) components, their
interactions and their microanatomical distribution is mandatory to better understand tumor …

Circulating tumor cells (CTCs) play a causal role in the development of metastasis, the major
cause of cancer-associated mortality worldwide. In the past decade, the development of …