Timely delivery of oxygen (O2) to tissue mitochondria is so essential that elaborate
circulatory systems have evolved to minimize diffusion distances within tissue. Yet …

Reactive oxygen species (ROS) are involved in biochemical processes such as redox
signaling, aging, carcinogenesis and neurodegeneration. Although biomembranes are …

Fluorescent probes have been employed for more than half a century to study the structure
and dynamics of model and biological membranes, using spectroscopic and/or microscopic …

Tachyplesin I, II and III are host defense peptides from horseshoe crab species with
antimicrobial and anticancer activities. They have an amphipathic β-hairpin structure, are …

Natamycin is a polyene macrolide, widely employed to treat fungal keratitis and other yeast
infections as well as to protect food products against fungal molds. In contrast to other …

Lipid peroxidation is a fundamental phenomenon in biology and medicine involved in a
wide range of diseases. Some key microscopic aspects of this reaction in cell membranes …

An understanding of the functional role played by a membrane-associated intrinsically
disordered protein (IDP) requires characterization of its heterogeneous conformations as …

Fluorescence spectroscopy provides numerous methodological tools for structural and
functional studies of biological macromolecules and their complexes. All fluorescence …

The appropriate lipid environment is crucial for the proper function of membrane proteins.
There is a tremendous variety of lipid molecules in the membrane and so far it is often …

Amphiphilic maleic acid-containing copolymers account for a recent methodical
breakthrough in the study of membrane proteins. Their application enables a detergent-free …