While summarizing the current understanding of how body temperature (Tb) is regulated,
this review discusses the recent progress in the following areas: central and peripheral …

Paracetamol (acetaminophen) is undoubtedly one of the most widely used drugs worldwide.
As an over-the-counter medication, paracetamol is the standard and first-line treatment for …

Fever is a common symptom of infectious and inflammatory disease. It is well-established
that prostaglandin E2 is the final mediator of fever, which by binding to its EP3 receptor …

This paper reviews the function, brain mechanisms and pharmacology of stress-induced
hyperthermia (SIH) in a broad context. Hyperthermia itself is induced by all stressful stimuli …

Fever is a cardinal symptom of infectious or inflammatory insults, but it can also arise from
noninfectious causes. The fever-inducing agent that has been used most frequently in …

Psychogenic fever is a stress-related, psychosomatic disease especially seen in young
women. Some patients develop extremely high core body temperature (Tc)(up to 41° C) …

Biosynthesis of prostanoids is regulated by three sequential enzymatic steps, namely
phospholipase $ A_2 $ enzymes, cyclooxygenase (COX) enzymes, and various lineage …

Abstract Prostaglandin E 2 (PGE 2) is a lipid mediator of inflammation and cancer
progression. It is mainly formed via metabolism of arachidonic acid by cyclooxygenases …

Prostaglandins (PGD2, PGE2, PGF2α), prostacyclin (PGI2), and thromboxane A2 (TXA2)
together form the prostanoid family of lipid mediators. As autacoids, these five primary …

Stress affects core body temperature (T c). Many kinds of stress induce transient,
monophasic hyperthermia, which diminishes gradually if the stressor is terminated. Stronger …