New halogen-containing drugs approved by FDA in 2021: An overview on their syntheses and pharmaceutical use

D Benedetto Tiz, L Bagnoli, O Rosati, F Marini… - Molecules, 2022 - mdpi.com
This review describes the recent Food and Drug Administration (FDA)-approved drugs (in
the year 2021) containing at least one halogen atom (covalently bound). The structures …

[HTML][HTML] Marine bacterial secondary metabolites: A treasure house for structurally unique and effective antimicrobial compounds

R Srinivasan, A Kannappan, C Shi, X Lin - Marine Drugs, 2021 - mdpi.com
The prevalence of antimicrobial resistance reduces the effectiveness of antimicrobial drugs
in preventing and treating infectious diseases caused by pathogenic organisms, such as …

An overview on the nutritional and bioactive components of green seaweeds

J Xu, W Liao, Y Liu, Y Guo, S Jiang, C Zhao - Food Production, Processing …, 2023 - Springer
Green seaweed, as the most abundant species of macroseaweeds, is an important marine
biological resource. It is a rich source of several amino acids, fatty acids, and dietary fibers …

[HTML][HTML] Rare rhizo-Actinomycetes: A new source of agroactive metabolites

OP Oyedoh, W Yang, D Dhanasekaran, G Santoyo… - Biotechnology …, 2023 - Elsevier
Numerous biotic and abiotic stress in some geographical regions predisposed their
agricultural matrix to challenges threatening plant productivity, health, and quality. In curbing …

Marine drugs: Biology, pipelines, current and future prospects for production

N Papon, BR Copp, V Courdavault - Biotechnology Advances, 2022 - Elsevier
The marine environment is a huge reservoir of biodiversity and represents an excellent
source of chemical compounds, some of which have large economical values. In the urgent …

The application of plant growth-promoting rhizobacteria in Solanum lycopersicum production in the agricultural system: a review

AA Adedayo, OO Babalola, C Prigent-Combaret… - PeerJ, 2022 - peerj.com
Food safety is a significant challenge worldwide, from plantation to cultivation, especially for
perishable products such as tomatoes. New eco-friendly strategies are needed, and …

Naturally occurring organohalogen compounds

GW Gribble - Accounts of Chemical Research, 1998 - Springer
The previous two surveys documented a combined total of 4714 naturally occurring
organohalogen compounds, both biogenic and abiotic [1, 2]. In the subsequent two …

[HTML][HTML] Structure-based pharmacophore modeling, virtual screening, molecular docking, ADMET, and molecular dynamics (MD) simulation of potential inhibitors of …

L Luo, A Zhong, Q Wang, T Zheng - Marine Drugs, 2021 - mdpi.com
Background: In the past decade, several antibodies directed against the PD-1/PD-L1
interaction have been approved. However, therapeutic antibodies also exhibit some …

Natural products from mangrove sediments-derived microbes: Structural diversity, bioactivities, biosynthesis, and total synthesis

K Li, S Chen, X Pang, J Cai, X Zhang, Y Liu… - European Journal of …, 2022 - Elsevier
The mangrove forests are a complex ecosystem, and the microbial communities in
mangrove sediments play a critical role in the biogeochemical cycles of mangrove …

Investigating the structure–activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors

A El-Demerdash, AA Al-Karmalawy, TM Abdel-Aziz… - RSC …, 2021 - pubs.rsc.org
Since its first report in December 2019, the novel coronavirus virus, SARS-CoV-2, has
caused an unprecedented global health crisis and economic loss imposing a tremendous …