Moonlighting chromatin: when DNA escapes nuclear control
J Singh, M Boettcher, M Dölling, A Heuer… - Cell Death & …, 2023 - nature.com
Extracellular chromatin, for example in the form of neutrophil extracellular traps (NETs), is an
important element that propels the pathological progression of a plethora of diseases. DNA …
important element that propels the pathological progression of a plethora of diseases. DNA …
Neutrophils' extracellular trap mechanisms: from physiology to pathology
J Schoen, M Euler, C Schauer, G Schett… - International Journal of …, 2022 - mdpi.com
Neutrophils are an essential part of the innate immune system and the first line of defense
against invading pathogens. They phagocytose, release granular contents, produce reactive …
against invading pathogens. They phagocytose, release granular contents, produce reactive …
Role and therapeutic targeting strategies of neutrophil extracellular traps in inflammation
Neutrophil extracellular traps (NETs) are large DNA reticular structures secreted by
neutrophils and decorated with histones and antimicrobial proteins. As a key mechanism for …
neutrophils and decorated with histones and antimicrobial proteins. As a key mechanism for …
Pathophysiology of meibomian glands–an overview
J Dietrich, F Garreis, F Paulsen - Ocular Immunology and …, 2021 - Taylor & Francis
Purpose: The meibomian glands are located in the tarsal plate of the upper and lower eyelid
and are responsible for the production of a lipid-rich secretion, the meibum, which forms the …
and are responsible for the production of a lipid-rich secretion, the meibum, which forms the …
Hypoxia promotes neutrophil survival after acute myocardial infarction
M Dölling, M Eckstein, J Singh, C Schauer… - Frontiers in …, 2022 - frontiersin.org
Phagocytosis, degranulation, and neutrophil extracellular traps (NETs) formation build the
armory of neutrophils for the first line of defense against invading pathogens. All these …
armory of neutrophils for the first line of defense against invading pathogens. All these …
DNases improve effectiveness of antibiotic treatment in murine polymicrobial sepsis
JF Willemsen, J Wenskus, M Lenz, H Rhode… - Frontiers in …, 2024 - frontiersin.org
Introduction Neutrophil extracellular traps (NETs) have various beneficial and detrimental
effects in the body. It has been reported that some bacteria may evade the immune system …
effects in the body. It has been reported that some bacteria may evade the immune system …
A comparative review of evaporative dry eye disease and meibomian gland dysfunction in dogs and humans
Dry eye disease is a complex ophthalmic disorder that consists of two main subtypes,
aqueous deficient dry eye (ADDE) and evaporative dry eye disease (EDED). Due to the …
aqueous deficient dry eye (ADDE) and evaporative dry eye disease (EDED). Due to the …
Neutrophil extracellular trap-driven occlusive diseases
The enlightenment of the formation of neutrophil extracellular traps (NETs) as a part of the
innate immune system shed new insights into the pathologies of various diseases. The initial …
innate immune system shed new insights into the pathologies of various diseases. The initial …
IL-8 triggers neutrophil extracellular trap formation through an nicotinamide adenine dinucleotide phosphate oxidase-and mitogen-activated protein kinase pathway …
Q Shu, N Zhang, Y Liu, X Wang, J Chen… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: To explore the mechanism underlying IL-8-induced neutrophil extracellular trap
(NET) formation in patients with ocular-active Behçet's disease (BD) and the effect of …
(NET) formation in patients with ocular-active Behçet's disease (BD) and the effect of …
Nanoparticles for stimulation of neutrophil extracellular trap‐mediated immunity
Neutrophil extracellular traps (NETs) have been identified as triggers for a self‐limited
inflammatory reaction upon contact with nanoparticles within our bodies. This typically …
inflammatory reaction upon contact with nanoparticles within our bodies. This typically …