Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and disease

L Hu, W Chen, A Qian, YP Li - Bone Research, 2024 - nature.com
Wnts are secreted, lipid-modified proteins that bind to different receptors on the cell surface
to activate canonical or non-canonical Wnt signaling pathways, which control various …

Matrix vesicle-mediated mineralization and osteocytic regulation of bone mineralization

T Hasegawa, H Hongo, T Yamamoto, M Abe… - International Journal of …, 2022 - mdpi.com
Bone mineralization entails two mineralization phases: primary and secondary
mineralization. Primary mineralization is achieved when matrix vesicles are secreted by …

Inflammatory macrophages interrupt osteocyte maturation and mineralization via regulating the Notch signaling pathway

S Wang, L ** application
Z Li, K ** using a variety of materials has been applied clinically to preserve the
health and vitality of the dental pulp and induce dentin repair no material meets all the anti …

Bone metastasis in endocrine-related cancer: unravelling invasion and destruction

HQ Duong, G Kafer… - Endocrine-Related …, 2025 - erc.bioscientifica.com
Bone is a common and debilitating site for metastatic cancer cell expansion. Skeletal
metastasis is a multistage process, with primary stages of circulating tumour cells …

Insights into the antiosteoporotic mechanism of the soy‐derived isoflavone genistein: Modulation of the Wnt/beta‐catenin signaling

F Mannino, C Imbesi, N Irrera, G Pallio, F Squadrito… - …, 2024 - Wiley Online Library
Bone remodeling is a process that involves osteoblasts, osteoclasts, and osteocytes, and
different intracellular signaling, such as the canonical Wnt/β‐catenin pathway …