Lactobacillus rhamnosus GG (LGG) was the first strain belonging to the genus Lactobacillus
to be patented in 1989 thanks to its ability to survive and to proliferate at gastric acid pH and …

Infections in the first year of life are common and often severe. The newborn host
demonstrates both quantitative and qualitative differences to the adult in nearly all aspects of …

More than 10,000 preterm infants have participated in randomised controlled trials on
probiotics worldwide, suggesting that probiotics in general could reduce rates of necrotising …

The growing number of antibiotic resistance genes is putting a strain on the ecosystem and
harming human health. In addition, consumers have developed a cautious attitude towards …

Perturbations to the infant gut microbiome during the first weeks to months of life affect
growth, development and health. In particular, assembly of an altered intestinal microbiota …

Background Lactoferrin, a normal component of human colostrum and milk, can enhance
host defenses and may be effective for prevention of sepsis and necrotizing enterocolitis …

Background & Aims We aimed to compare the effectiveness of single-vs multiple-strain
probiotics in a network meta-analysis of randomized trials. Methods We searched MEDLINE …

Background Intestinal dysbiosis may contribute to the pathogenesis of necrotising
enterocolitis (NEC) in very preterm or very low birth weight infants. Dietary supplementation …

Lactoferrin (Lf), an iron-binding multifunctional glycoprotein belonging to the transferrin
family, is present in most biological secretions and reaches particularly high concentrations …

The diversity of probiotic products makes choosing an appropriate probiotic challenging.
One unanswered question is whether single-strain probiotics are more effective than multi …