The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …

Zika virus (ZIKV) infection during pregnancy has emerged as a global public health problem
because of its ability to cause severe congenital disease. Here, we developed six mouse …

Dengue virus poses a major threat to global public health: two-thirds of the world's
population is now at risk from infection by this mosquito-borne virus. Dengue virus causes a …

Dengue is the most common viral infection spread by mosquitoes, prevalent in tropical
countries. The acute dengue virus (DENV) infection is a benign and primarily febrile illness …

Sensitization of the humoral immune response to invading viruses and production of
antiviral antibodies forms part of the host antiviral repertoire. Paradoxically, for a number of …

Antibodies protect against homologous Dengue virus (DENV) infection but can precipitate
severe dengue by promoting heterotypic virus entry via Fcγ receptors (FcγR). We …

Dengue is a mosquito-borne flavivirus that is spreading at an unprecedented rate and has
developed into a major health and economic burden in over 50 countries. Even though …

Dengue viruses (DENV) are the causative agents of dengue fever (DF) and dengue
hemorrhagic fever (DHF). Here we review the current state of knowledge about the human …

Antibodies are an important component in host immune responses to viral pathogens.
Because of their unique maturation process, antibodies can evolve to be highly specific to …