The A3 adenosine receptor (A3AR) subtype is a novel, promising therapeutic target for
inflammatory diseases, such as rheumatoid arthritis (RA) and psoriasis, as well as liver …

The regulatory actions of adenosine are mediated via four subtypes of G protein-coupled
receptors distinguished as A 1, A 2A, A 2B and A 3 receptors. Their presence on basically …

A neuroprotective role for adenosine is commonly assumed. Recent studies revealed that
adenosine may unexpectedly, under certain circumstances, have the opposite effects …

Key points Brief dopamine events are critical actors of reward‐mediated learning in the
striatum; the intracellular cAMP–protein kinase A (PKA) response of striatal medium spiny …

Imiquimod, a small-molecule immune response modifier of the imidazoquinoline family, has
shown profound antitumoral and antiviral efficacy both in vitro and in clinical applications in …

Traditionally, platelets are known to play an important role in haemostasis and thrombosis;
however, they serve also as important modulators of inflammation and immunity. Platelets …

Adenosine is a physiological nucleoside which acts as an autocoid and activates G protein-
coupled membrane receptors, designated A1, A2A, A2B and A3. Adenosine plays an …

Intense efforts of many pharmaceutical companies and academicians in the A 1 adenosine
receptor (AR) field have led to the discovery of clinical candidates that are antagonists …

1 Two human breast cancer cell lines, MCF‐7 and MDA‐MB‐231, were screened for the
presence of functionally significant adenosine receptor subtypes. 2 MCF‐7 cells did not …

Adenosine exerts its effects through four subtypes of G-protein-coupled receptors: A 1, A 2A,
A 2B, and A 3. Stimulation of the human A 3 receptor has been suggested to influence cell …