Bone has a complex hierarchical structure with structural integration from nm to cm. The
understanding of bone structure is develo** rapidly due to improvements in available …

Featured Application The focus of this review is the use of SEM imaging to gain insight into
the composition and morphology of minerals in view of predicting or understanding their …

Vertebrate Skeletal Histology and Paleohistology summarizes decades of research into the
biology and biological meaning of hard tissues, in both living and extinct vertebrates. In …

Structural hierarchy of bone–observed across multiple scales and in three dimensions (3D)–
is essential to its mechanical performance. While the mineralized extracellular matrix of …

The formation of the hard tissues that provide support and mobility to organisms is achieved
through the interplay of inorganic crystals and an organic framework composed of collagen …

Much debate still revolves around bone architecture, especially at the nano-and microscale.
Bone is a remarkable material where high strength and toughness coexist thanks to an …

We review here the Stenciling Principle for extracellular matrix mineralization that describes
a double-negative process (inhibition of inhibitors) that promotes mineralization in bone and …

Biominerals and biomaterials are part of our daily lives, from our skeleton and teeth to coral
reefs and carbon-capturing single-cell organisms in the oceans, to engineered ceramics …

Given the hierarchical nature of bone and bone interfaces, osseointegration, namely the
formation of a direct bone-implant contact, is best evaluated using a multiscale approach …

Mineralized collagen fibrils are the building block units of bone at the nanoscale. While it is
known that collagen fibrils are mineralized both inside their gap zones (intra-fibrillar …