The crucial role and mechanism of insulin resistance in metabolic disease

X Zhao, X An, C Yang, W Sun, H Ji… - Frontiers in endocrinology, 2023 - frontiersin.org
Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …

Obstructive sleep apnea in cardiovascular disease: a review of the literature and proposed multidisciplinary clinical management strategy

JR Tietjens, D Claman, EJ Kezirian… - Journal of the …, 2019 - Am Heart Assoc
Cardiovascular disease (CVD) remains a highly prevalent cause of morbidity and mortality,
both in the United States and worldwide. In parallel with the development of new and …

Adult obstructive sleep apnoea

AS Jordan, DG McSharry, A Malhotra - The Lancet, 2014 - thelancet.com
Obstructive sleep apnoea is an increasingly common disorder of repeated upper airway
collapse during sleep, leading to oxygen desaturation and disrupted sleep. Features include …

Pathophysiology of human visceral obesity: an update

A Tchernof, JP Després - Physiological reviews, 2013 - journals.physiology.org
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

CPAP, weight loss, or both for obstructive sleep apnea

JA Chirinos, I Gurubhagavatula, K Teff… - … England Journal of …, 2014 - Mass Medical Soc
Background Obesity and obstructive sleep apnea tend to coexist and are associated with
inflammation, insulin resistance, dyslipidemia, and high blood pressure, but their causal …

Interactions between obesity and obstructive sleep apnea: implications for treatment

A Romero-Corral, SM Caples, F Lopez-Jimenez… - Chest, 2010 - Elsevier
Obstructive sleep apnea (OSA) adversely affects multiple organs and systems, with
particular relevance to cardiovascular disease. Several conditions associated with OSA …

Sleep apnea and cardiovascular disease: An American heart association/American college of cardiology foundation scientific statement from the American heart …

VK Somers, DP White, R Amin, WT Abraham, F Costa… - Circulation, 2008 - Am Heart Assoc
Experimental approaches directed at addressing these issues are limited by several
considerations. First, the close association between obesity and OSA often obscures …

Obstructive sleep apnea, hypoxia, and nonalcoholic fatty liver disease

OA Mesarwi, R Loomba, A Malhotra - American journal of …, 2019 - atsjournals.org
Recent studies have demonstrated that obstructive sleep apnea (OSA) is associated with the
development and evolution of nonalcoholic fatty liver disease (NAFLD), independent of …

Neurocognitive function in obstructive sleep apnoea: A meta‐review

RS Bucks, M Olaithe, P Eastwood - Respirology, 2013 - Wiley Online Library
Adult obstructive sleep apnoea (OSA) is associated with cognitive dysfunction. While many
review articles have attempted to summarize the evidence for this association, it remains …

Obstructive sleep apnoea syndrome

P Lévy, M Kohler, WT McNicholas, F Barbé… - Nature reviews Disease …, 2015 - nature.com
Obstructive sleep apnoea syndrome (OSAS) is a common clinical condition in which the
throat narrows or collapses repeatedly during sleep, causing obstructive sleep apnoea …