Oxytocin pathway genes: evolutionary ancient system impacting on human affiliation, sociality, and psychopathology

R Feldman, M Monakhov, M Pratt, RP Ebstein - Biological psychiatry, 2016‏ - Elsevier
Oxytocin (OT), a nonapeptide signaling molecule originating from an ancestral peptide,
appears in different variants across all vertebrate and several invertebrate species …

[HTML][HTML] Autism, oxytocin and interoception

E Quattrocki, K Friston - Neuroscience & Biobehavioral Reviews, 2014‏ - Elsevier
Autism is a pervasive developmental disorder characterized by profound social and verbal
communication deficits, stereotypical motor behaviors, restricted interests, and cognitive …

Oxytocin receptor is not required for social attachment in prairie voles

KM Berendzen, R Sharma, MA Mandujano, Y Wei… - Neuron, 2023‏ - cell.com
Prairie voles are among a small group of mammals that display long-term social attachment
between mating partners. Many pharmacological studies show that signaling via the …

Neuromodulation by oxytocin and vasopressin

R Stoop - Neuron, 2012‏ - cell.com
Oxytocin (OT) and vasopressin (VP) are two closely related neuropeptides, widely known for
their peripheral hormonal effects. Specific receptors have also been found in the brain …

Global view of the evolution and diversity of metazoan neuropeptide signaling

G Jékely - Proceedings of the National Academy of Sciences, 2013‏ - pnas.org
Neuropeptides are signaling molecules that commonly act via G protein-coupled receptors
(GPCRs) and are generated in neurons by proneuropeptide (pNP) cleavage. Present in both …

[HTML][HTML] What is a pair bond?

KL Bales, CS Ardekani, A Baxter, CL Karaskiewicz… - Hormones and …, 2021‏ - Elsevier
Pair bonding is a psychological construct that we attempt to operationalize via behavioral
and physiological measurements. Yet, pair bonding has been both defined differently in …

Neuromodulation of circuits with variable parameters: single neurons and small circuits reveal principles of state-dependent and robust neuromodulation

E Marder, T O'Leary, S Shruti - Annual review of neuroscience, 2014‏ - annualreviews.org
Neuromodulation underlies many behavioral states and has been extensively studied in
small circuits. This has allowed the systematic exploration of how neuromodulatory …

Oxytocin/vasopressin-related peptides have an ancient role in reproductive behavior

JL Garrison, EZ Macosko, S Bernstein, N Pokala… - Science, 2012‏ - science.org
Many biological functions are conserved, but the extent to which conservation applies to
integrative behaviors is unknown. Vasopressin and oxytocin neuropeptides are strongly …

An evolutionary framework for studying mechanisms of social behavior

HA Hofmann, AK Beery, DT Blumstein… - Trends in ecology & …, 2014‏ - cell.com
Social interactions are central to most animals and have a fundamental impact upon the
phenotype of an individual. Social behavior (social interactions among conspecifics) …

The neuroanatomical distribution of oxytocin receptor binding and mRNA in the male rhesus macaque (Macaca mulatta)

SM Freeman, K Inoue, AL Smith, MM Goodman… - …, 2014‏ - Elsevier
The rhesus macaque (Macaca mulatta) is an important primate model for social cognition,
and recent studies have begun to explore the impact of oxytocin on social cognition and …