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Evolution and diversity of assembly-line polyketide synthases: focus review
Assembly-line polyketide synthases (PKSs) are among the most complex protein
machineries known in nature, responsible for the biosynthesis of numerous compounds …
machineries known in nature, responsible for the biosynthesis of numerous compounds …
Evolutionary pathways and trajectories in antibiotic resistance
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …
provided a wealth of information, but knowledge regarding “what happened” has precluded …
The overlooked evolutionary dynamics of 16S rRNA revises its role as the “gold standard” for bacterial species identification
O Bartoš, M Chmel, I Swierczková - Scientific Reports, 2024 - nature.com
The role of 16S rRNA has been and largely remains crucial for the identification of microbial
organisms. Although 16S rRNA could certainly be described as one of the most studied …
organisms. Although 16S rRNA could certainly be described as one of the most studied …
Bacterial genome instability
E Darmon, DRF Leach - Microbiology and Molecular Biology …, 2014 - journals.asm.org
Bacterial genomes are remarkably stable from one generation to the next but are plastic on
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …
Hydrolytic endonucleolytic ribozyme (HYER) is programmable for sequence-specific DNA cleavage
Ribozymes are catalytic RNAs with diverse functions including self-splicing and
polymerization. This work aims to discover natural ribozymes that behave as hydrolytic and …
polymerization. This work aims to discover natural ribozymes that behave as hydrolytic and …
The role of abiotic factors modulating the plant-microbe-soil interactions: toward sustainable agriculture. A review
Microbial soil communities are active players in the biogeochemical cycles, impacting soil
fertility and interacting with aboveground organisms. Although soil microbial diversity has …
fertility and interacting with aboveground organisms. Although soil microbial diversity has …
A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesis
Bacterial secondary metabolites are widely used as antibiotics, anticancer drugs,
insecticides and food additives. Attempts to engineer their biosynthetic gene clusters (BGCs) …
insecticides and food additives. Attempts to engineer their biosynthetic gene clusters (BGCs) …
Evolutionary dynamics of natural product biosynthesis in bacteria
Covering: 2008 up to 2019 The forces of biochemical adaptive evolution operate at the level
of genes, manifesting in complex phenotypes and the global biodiversity of proteins and …
of genes, manifesting in complex phenotypes and the global biodiversity of proteins and …
Regulated polyploidy in halophilic archaea
Polyploidy is common in higher eukaryotes, especially in plants, but it is generally assumed
that most prokaryotes contain a single copy of a circular chromosome and are therefore …
that most prokaryotes contain a single copy of a circular chromosome and are therefore …
Biological applications of the theory of birth-and-death processes
In this review, we discuss applications of the theory of birth-and-death processes to
problems in biology, primarily, those of evolutionary genomics. The mathematical principles …
problems in biology, primarily, those of evolutionary genomics. The mathematical principles …