[HTML][HTML] Type I interferons in infectious disease
Type I interferons (IFNs) have diverse effects on innate and adaptive immune cells during
infection with viruses, bacteria, parasites and fungi, directly and/or indirectly through the …
infection with viruses, bacteria, parasites and fungi, directly and/or indirectly through the …
The interferon (IFN) class of cytokines and the IFN regulatory factor (IRF) transcription factor family
H Negishi, T Taniguchi, H Yanai - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Interferons (IFNs) are a broad class of cytokines elicited on challenge to the host defense
and are essential for mobilizing immune responses to pathogens. Divided into three classes …
and are essential for mobilizing immune responses to pathogens. Divided into three classes …
Can SARS-CoV-2 virus use multiple receptors to enter host cells?
The occurrence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …
Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways
D Zhou, C Huang, Z Lin, S Zhan, L Kong, C Fang, J Li - Cellular signalling, 2014 - Elsevier
Monocytes/macrophages are heterogeneous and versatile cells that could undergo their
phenotypically/functionally dynamic switch in response to the microenvironment signals …
phenotypically/functionally dynamic switch in response to the microenvironment signals …
Transcriptional regulation of macrophage polarization: enabling diversity with identity
In terms of both phenotype and function, macrophages have remarkable heterogeneity,
which reflects the specialization of tissue-resident macrophages in microenvironments as …
which reflects the specialization of tissue-resident macrophages in microenvironments as …
The roles of type I interferon in bacterial infection
Type I interferons (IFNs) are pleiotropic cytokines well recognized for their role in the
induction of a potent antiviral gene program essential for host defense against viruses. They …
induction of a potent antiviral gene program essential for host defense against viruses. They …
Sources of type I interferons in infectious immunity: plasmacytoid dendritic cells not always in the driver's seat
Type I Interferons (IFNs) are hallmark cytokines produced in immune responses to all
classes of pathogens. Type I IFNs can influence dendritic cell (DC) activation, maturation …
classes of pathogens. Type I IFNs can influence dendritic cell (DC) activation, maturation …
The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and …
Type I interferons (IFNs) are central regulators of the innate and adaptive immune responses
to viral and bacterial infections. Type I IFNs are induced upon cytosolic detection of microbial …
to viral and bacterial infections. Type I IFNs are induced upon cytosolic detection of microbial …
Listeria monocytogenes induces IFNβ expression through an IFI16‐, cGAS‐ and STING‐dependent pathway
K Hansen, T Prabakaran, A Laustsen… - The EMBO …, 2014 - embopress.org
Listeria monocytogenes is a gram‐positive facultative intracellular bacterium, which
replicates in the cytoplasm of myeloid cells. Interferon β (IFNβ) has been reported to play an …
replicates in the cytoplasm of myeloid cells. Interferon β (IFNβ) has been reported to play an …
Genomic and pathogenicity islands of Listeria monocytogenes—overview of selected aspects
N Wiktorczyk-Kapischke, K Skowron… - Frontiers in Molecular …, 2023 - frontiersin.org
Listeria monocytogenes causes listeriosis, a disease characterized by a high mortality rate
(up to 30%). Since the pathogen is highly tolerant to changing conditions (high and low …
(up to 30%). Since the pathogen is highly tolerant to changing conditions (high and low …