ROC curve analysis is often applied to measure the diagnostic accuracy of a biomarker. The
analysis results in two gains: diagnostic accuracy of the biomarker and the optimal cut‐point …

Introduction We examined and compared plasma phospho-tau181 (pTau181) and total
tau:(1) across the Alzheimer's disease (AD) clinical spectrum;(2) in relation to brain amyloid …

Importance Radiotherapy accelerates coronary heart disease (CHD), but the dose to critical
cardiac substructures has not been systematically studied in lung cancer. Objective To …

Background: Radiotherapy-associated cardiac toxicity studies in patients with locally
advanced non–small cell lung cancer (NSCLC) have been limited by small sample size and …

The associations between visceral adiposity index (VAI), body shape index and diabetes in
adults were inconsistent. We assessed the predictive capacity of VAI and body shape index …

Background Cardiac surgery is associated with a high risk of postoperative acute kidney
injury (AKI) and subsequent loss of kidney function. We explored the clinical utility of urinary …

Objective Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease
associated with exposure to contact and collision sports, including American football. We …

Introduction The choice of criteria in determining optimal cut-off value is a matter of concern
in quantitative diagnostic tests. Several indexes such as Youden's index, Euclidean index …

Introduction An important application of ROC analysis is the determination of the optimal cut-
point for biomarkers in diagnostic studies. This comprehensive review provides a framework …

Introduction Survivors of COVID-19 infection may develop post-covid pulmonary fibrosis
(PCF) and suffer from long term multi-system complications. The magnitude and risk factors …