Peripheral muscle dysfunction is an important systemic consequence of cystic fibrosis (CF)
with major clinical implications, such as exercise intolerance and reduced quality of life …

Fully updated, revised and consolidated into one single volume, the fourth edition of
Kinanthropometry and Exercise Physiology offers the best theoretically contextualised …

New Findings What is the topic of this review? This review highlights the central and
peripheral mechanisms that alter oxygen transport and utilisation and thereby contribute to …

New Findings What is the central question of this study? Do intrinsic abnormalities in
oxygenation and/or muscle oxidative metabolism contribute to exercise intolerance in …

PURPOSE: To characterise changes in deoxyhemoglobin ([HHb]) response dynamics in
boys and girls during ramp incremental exercise to investigate whether the reduced peak …

Background Increased maximal oxygen uptake (V̇O2max) is beneficial in children with
cystic fibrosis (CF) but remains lower compared to healthy peers. Intrinsic metabolic …

PURPOSE: To investigate the effects of mild-to-moderate cystic fibrosis (CF) on the
pulmonary oxygen uptake (V˙ O2) kinetics of 7 pediatric patients (13.5±2.8 y) versus 7 …

Purpose: Exercise intolerance, evaluated by O2 consumption, predicts mortality in Cystic
Fibrosis (CF). People with CF exhibit skeletal muscle dysfunctions that may contribute to an …

Background While exercise testing is increasingly used as a prognostic indicator in cystic
fibrosis (CF), it is reported to be underused in UK CF centres, particularly in children. Here …

ABSTRACT Background and Objectives Patients with primary ciliary dyskinesia (PCD) have
a reduction in exercise capacity from the early stages. Although there are studies …