Neurotrophic factors, particularly BDNF (brain-derived neurotrophic factor), have been
associated with depression and antidepressant drug action. A variety of preclinical and …

Major depression is a leading contributor to the global burden of disease. This situation is
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …

The mechanisms underlying the pathophysiology and treatment of depression and stress-
related disorders remain unclear, but studies in depressed patients and rodent models are …

Depression is a common, devastating illness. Current pharmacotherapies help many
patients, but high rates of a partial response or no response, and the delayed onset of the …

This meta-analysis evaluated the relation between social support and depression in youth
and compared the cumulative evidence for 2 theories that have been proposed to explain …

The pathophysiology and treatment of depression have been the focus of intense research
and while there is much that remains unknown, modern neurobiological approaches are …

Depressive disorders (DDs) are one of the most widespread forms of psychiatric pathology.
According to the World Health Organization, about 350 million people in the world are …

We propose that depression can be viewed as an adaptation to conserve energy after the
perceived loss of an investment in a vital resource such as a relationship, group identity, or …

The goal of the present protocol is to describe the forced swim test (FST), which is one of the
most commonly used assays for the study of depressive-like behavior in rodents. The FST is …

Resilience science is quintessential developmental psychopathology because it focuses on
variation among individuals in relation to their experiences as they adapt and develop …