Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024‏ - nature.com
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Microbiome and human health: current understanding, engineering, and enabling technologies

N Aggarwal, S Kitano, GRY Puah, S Kittelmann… - Chemical …, 2022‏ - ACS Publications
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

Microbiota in health and diseases

K Hou, ZX Wu, XY Chen, JQ Wang, D Zhang… - Signal transduction and …, 2022‏ - nature.com
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

Pathogenesis of pneumonia and acute lung injury

ME Long, RK Mallampalli, JC Horowitz - Clinical Science, 2022‏ - portlandpress.com
Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …

[HTML][HTML] Microbes, metabolites, and the gut–lung axis

AT Dang, BJ Marsland - Mucosal immunology, 2019‏ - Elsevier
The microbiota plays an essential role in the education, development, and function of the
immune system, both locally and systemically. Emerging experimental and epidemiological …

The influence of the microbiome on respiratory health

TP Wypych, LC Wickramasinghe, BJ Marsland - Nature immunology, 2019‏ - nature.com
The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …

The role of lung and gut microbiota in the pathology of asthma

W Barcik, RCT Boutin, M Sokolowska, BB Finlay - Immunity, 2020‏ - cell.com
Asthma is a common chronic respiratory disease affecting more than 300 million people
worldwide. Clinical features of asthma and its immunological and molecular etiology vary …

Dysbiosis of the gut and lung microbiome has a role in asthma

K Hufnagl, I Pali-Schöll, F Roth-Walter… - Seminars in …, 2020‏ - Springer
Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …

The lung microbiome during health and disease

K Yagi, GB Huffnagle, NW Lukacs, N Asai - International Journal of …, 2021‏ - mdpi.com
Healthy human lungs have traditionally been considered to be a sterile organ. However,
culture-independent molecular techniques have reported that large numbers of microbes …

The gut–airway microbiome axis in health and respiratory diseases

M Özçam, SV Lynch - Nature Reviews Microbiology, 2024‏ - nature.com
Communication between the gut and remote organs, such as the brain or the cardiovascular
system, has been well established and recent studies provide evidence for a potential …