The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …

Chemokines are chemotactic cytokines that control the migration and positioning of immune
cells in tissues and are critical for the function of the innate immune system. Chemokines …

Neutrophils, the most abundant human immune cells, are rapidly recruited to sites of
infection, where they fulfill their life-saving antimicrobial functions. While traditionally …

Chemokines are recognized as the most critical mediators for selective neutrophil
recruitment during inflammatory conditions. Furthermore, they are considered fundamental …

Chemokines are chemo tactic cyto kines that control the migratory patterns and positioning
of all immune cells. Although chemokines were initially appreciated as important mediators …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Neutrophils are a major component of the innate immune response. Their homeostasis is
maintained, in part, by the regulated release of neutrophils from the bone marrow …

The chemokine receptor CXCR4 belongs to the large superfamily of G protein-coupled
receptors, and is directly involved in a number of biological processes including …

For the past twenty years, chemokines have emerged as a family of critical mediators of cell
migration during immune surveillance, development, inflammation and cancer progression …

Background Chemokines play a critical role in orchestrating the distribution and trafficking of
neutrophils in homeostasis and disease. Results The CXCR 4/CXCL 12 chemokine axis has …