The changing opioid crisis: development, challenges and opportunities
ND Volkow, C Blanco - Molecular psychiatry, 2021 - nature.com
The current opioid epidemic is one of the most severe public health crisis in US history.
Responding to it has been difficult due to its rapidly changing nature and the severity of its …
Responding to it has been difficult due to its rapidly changing nature and the severity of its …
Neurobiology of addiction: a neurocircuitry analysis
GF Koob, ND Volkow - The Lancet Psychiatry, 2016 - thelancet.com
Drug addiction represents a dramatic dysregulation of motivational circuits that is caused by
a combination of exaggerated incentive salience and habit formation, reward deficits and …
a combination of exaggerated incentive salience and habit formation, reward deficits and …
The effect of online restaurant menus on consumers' purchase intentions during the COVID-19 pandemic
As COVID-19 escalated globally in 2020, mandated suspension of dine-in services was
instilled to control virus transmission. Restaurants lost billions of dollars, millions …
instilled to control virus transmission. Restaurants lost billions of dollars, millions …
Obesity as a disease
Obesity is a complex, chronic medical condition with a major negative impact on human
health. 1 Over the last 30 years, there has been an exponential growth in the prevalence of …
health. 1 Over the last 30 years, there has been an exponential growth in the prevalence of …
Food cue reactivity and craving predict eating and weight gain: a meta‐analytic review
According to learning‐based models of behavior, food cue reactivity and craving are
conditioned responses that lead to increased eating and subsequent weight gain. However …
conditioned responses that lead to increased eating and subsequent weight gain. However …
[HTML][HTML] Stress and eating behaviors
Obesity is a heterogeneous construct that, despite multiple and diverse attempts, has been
difficult to treat. One conceptualization gaining media and research attention in recent years …
difficult to treat. One conceptualization gaining media and research attention in recent years …
Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications
RZ Goldstein, ND Volkow - Nature reviews neuroscience, 2011 - nature.com
The loss of control over drug intake that occurs in addiction was initially believed to result
from disruption of subcortical reward circuits. However, imaging studies in addictive …
from disruption of subcortical reward circuits. However, imaging studies in addictive …
Nonalcoholic fatty liver disease: pathophysiology and management
Nonalcoholic fatty liver disease (NAFLD) is a clinical diagnosis that includes the presence of
5% or more hepatic steatosis as determined by liver imaging or biopsy in the absence of …
5% or more hepatic steatosis as determined by liver imaging or biopsy in the absence of …
Obesity and addiction: neurobiological overlaps
Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …
disorders in which the saliency of a specific type of reward (food or drug) becomes …
Why is obesity such a problem in the 21st century? The intersection of palatable food, cues and reward pathways, stress, and cognition
Abstract Changes in food composition and availability have contributed to the dramatic
increase in obesity over the past 30–40 years in developed and, increasingly, in develo** …
increase in obesity over the past 30–40 years in developed and, increasingly, in develo** …