Polymerase chain reaction (PCR)‐based nucleic acid testing has played a critical role in
disease diagnostics, pathogen surveillance, and many more. However, this method requires …

CRISPR systems mediate adaptive immunity in bacteria and archaea through diverse
effector mechanisms and have been repurposed for versatile applications in therapeutics …

Recent advances in biointerfaces have led to the development of wearable devices that can
provide insights into personal health. As wearable modules, microneedles can extract …

CRISPR/Cas system is becoming an increasingly influential technology that has been
repositioned in nucleic acid detection. A preamplification step is usually required to improve …

Nucleic acids, including circulating tumor DNA (ctDNA), microRNA, and virus DNA/RNA,
have been widely applied as potential disease biomarkers for early clinical diagnosis. In this …

Methicillin-resistant Staphylococcus aureus (MRSA), a common zoonotic multidrug-resistant
bacterium, puts a great threat to public health and food safety. Rapid and reliable detection …

Infectious diseases continue to pose an imminent threat to global public health, leading to
high numbers of deaths every year and disproportionately impacting develo** countries …

The CRISPR-Cas system was developed into a molecular diagnostic tool with high
sensitivity, low cost, and high specificity in recent years. Colorimetric assays based on …

The CRISPR/Cas system is a protective adaptive immune system against attacks from
foreign mobile genetic elements. Since the discovery of the excellent target-specific …

Microorganisms have gained defense systems during the lengthy process of evolution over
millions of years. Such defense systems can protect them from being attacked by invading …