Impaired glucose homeostasis in first-episode schizophrenia: a systematic review and meta-analysis

T Pillinger, K Beck, C Gobjila, JG Donocik… - JAMA …, 2017 - jamanetwork.com
Importance Schizophrenia is associated with an increased risk of type 2 diabetes. However,
it is not clear whether schizophrenia confers an inherent risk for glucose dysregulation in the …

Toward a unified theory of childhood trauma and psychosis: a comprehensive review of epidemiological, clinical, neuropsychological and biological findings

B Misiak, M Krefft, T Bielawski, AA Moustafa… - Neuroscience & …, 2017 - Elsevier
There is a growing body of research focused on the relationship between childhood trauma
and the risk of develo** psychosis. Numerous studies, including many large-scale …

The association between first-episode psychosis and abnormal glycaemic control: systematic review and meta-analysis

BI Perry, G McIntosh, S Weich, S Singh… - The Lancet Psychiatry, 2016 - thelancet.com
Background Schizophrenia might share intrinsic inflammatory disease pathways with type 2
diabetes. We aimed to assess whether first-episode psychosis, which could be described as …

Cholesterol and triglyceride levels in first-episode psychosis: systematic review and meta-analysis

T Pillinger, K Beck, B Stubbs… - The British Journal of …, 2017 - cambridge.org
Background The extent of metabolic and lipid changes in first-episode psychosis (FEP) is
unclear. Aims To investigate whether individuals with FEP and no or minimal antipsychotic …

Lipid profile disturbances in antipsychotic-naive patients with first-episode non-affective psychosis: A systematic review and meta-analysis

B Misiak, B Stańczykiewicz, Ł Łaczmański… - Schizophrenia …, 2017 - Elsevier
Background Dyslipidaemia is one of the most prevalent metabolic disturbances observed in
schizophrenia patients and has been largely attributed to the effects of poor lifestyle habits …

drug‐induced liver injury in the context of nonalcoholic fatty liver disease–a physiopathological and clinical integrated view

F Bessone, M Dirchwolf, MA Rodil… - Alimentary …, 2018 - Wiley Online Library
Background Nonalcoholic fatty disease (NAFLD) is the most common liver disease, since it
is strongly associated with obesity and metabolic syndrome pandemics. NAFLD may affect …

Meta-analysis of glucose tolerance, insulin, and insulin resistance in antipsychotic-naïve patients with nonaffective psychosis

AM Greenhalgh, L Gonzalez-Blanco… - Schizophrenia …, 2017 - Elsevier
Background Some studies have suggested that antipsychotic-naïve patients with
nonaffective psychosis (NAP) have glucose intolerance. Aims To conduct a systematic …

Intrinsic and antipsychotic drug-induced metabolic dysfunction in schizophrenia

Z Freyberg, D Aslanoglou, R Shah… - Frontiers in …, 2017 - frontiersin.org
For decades, there have been observations demonstrating significant metabolic
disturbances in people with schizophrenia including clinically relevant weight gain …

Glucose disturbances, cognitive deficits and white matter abnormalities in first-episode drug-naive schizophrenia

X Zhang, M Yang, X Du, W Liao, D Chen, F Fan… - Molecular …, 2020 - nature.com
Disturbance of glucose metabolism may be implicated in cognitive deficits of schizophrenia
in its early phases. Many studies have reported the important role of widespread disruption …

Meta-analysis of blood cortisol levels in individuals with first-episode psychosis

DB Hubbard, BJ Miller - Psychoneuroendocrinology, 2019 - Elsevier
Objective Schizophrenia is associated with abnormal neuroimmunoendocrine function.
There is evidence for hypothalamic-pituitary-adrenal (HPA) axis abnormalities in individuals …