Genome-resolved metagenomics: a game changer for microbiome medicine

N Kim, J Ma, W Kim, J Kim, P Belenky… - Experimental & Molecular …, 2024 - nature.com
Recent substantial evidence implicating commensal bacteria in human diseases has given
rise to a new domain in biomedical research: microbiome medicine. This emerging field …

[HTML][HTML] Mediterranean diet and olive oil, microbiota, and obesity-related cancers. From mechanisms to prevention

E Almanza-Aguilera, A Cano, M Gil-Lespinard… - Seminars in Cancer …, 2023 - Elsevier
Olive oil (OO) is the main source of added fat in the Mediterranean diet (MD). It is a mix of
bioactive compounds, including monounsaturated fatty acids, phytosterols, simple phenols …

Single-cell transcriptomics across 2,534 microbial species reveals functional heterogeneity in the rumen microbiome

M Jia, S Zhu, MY Xue, H Chen, J Xu, M Song… - Nature …, 2024 - nature.com
Deciphering the activity of individual microbes within complex communities and
environments remains a challenge. Here we describe the development of microbiome single …

A metagenomic catalog of the early-life human gut virome

S Zeng, A Almeida, S Li, J Ying, H Wang, Y Qu… - Nature …, 2024 - nature.com
Early-life human gut microbiome is a pivotal driver of gut homeostasis and infant health.
However, the viral component (known as “virome”) remains mostly unexplored. Here, we …

Fast and robust metagenomic sequence comparison through sparse chaining with skani

J Shaw, YW Yu - Nature Methods, 2023 - nature.com
Sequence comparison tools for metagenome-assembled genomes (MAGs) struggle with
high-volume or low-quality data. We present skani (https://github. com/bluenote-1577/skani) …

SemiBin2: self-supervised contrastive learning leads to better MAGs for short-and long-read sequencing

S Pan, XM Zhao, LP Coelho - Bioinformatics, 2023 - academic.oup.com
Motivation Metagenomic binning methods to reconstruct metagenome-assembled genomes
(MAGs) from environmental samples have been widely used in large-scale metagenomic …

The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications—2023 Diabetes, Diabetes Care, and Diabetologia Expert Forum

M Byndloss, S Devkota, F Duca, JH Niess… - Diabetes, 2024 - diabetesjournals.org
This article summarizes the state of the science on the role of the gut microbiota (GM) in
diabetes from a recent international expert forum organized by Diabetes, Diabetes Care …

Lipid Metabolites as Potential Regulators of the Antibiotic Resistome in Tetramorium caespitum

MK **, Q Zhang, N Xu, Z Zhang, HQ Guo… - Environmental …, 2024 - ACS Publications
Antibiotic resistance genes (ARGs) are ancient but have become a modern critical threat to
health. Gut microbiota, a dynamic reservoir for ARGs, transfer resistance between …

A comprehensive genomic catalog from global cold seeps

Y Han, C Zhang, Z Zhao, Y Peng, J Liao, Q Jiang, Q Liu… - Scientific Data, 2023 - nature.com
Cold seeps harbor abundant and diverse microbes with tremendous potential for biological
applications and that have a significant influence on biogeochemical cycles. Although recent …

[HTML][HTML] Metabolic engineering of human gut microbiome: recent developments and future perspectives

P Li, S Roos, H Luo, B Ji, J Nielsen - Metabolic Engineering, 2023 - Elsevier
Many studies have demonstrated that the gut microbiota is associated with human health
and disease. Manipulation of the gut microbiota, eg supplementation of probiotics, has been …