Anticoagulant drugs antagonize coagulation and are used to prevent or cure (recurrent)
venous thromboembolism (VTE). Drugs to prevent clotting have been used for more than a …

Abstract Aim The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management
of Patients With Atrial Fibrillation” provides recommendations to guide clinicians in the …

The European Association for Cardio-Thoracic Surgery (EACTS) established a
multidisciplinary task force of experts involved in perioperative and long-term care of …

ABSTRACT Introduction Proton pump inhibitors (PPIs) block the gastric H/K-ATPase,
therefore inhibiting acid gastric secretion, leading to an increased pH (> 4). They account for …

Cardiac surgery is a distinctive surgical discipline that often necessitates the use of
cardiopulmonary bypass (CPB) and full anticoagulation intraoperatively, along with varying …

Anticoagulant surface modification of blood-contacting materials has been shown to be
effective in preventing thrombosis and reducing the dose of anticoagulant drugs that patients …

Aims The evidence of a protective effect of proton‐pump inhibitor (PPI) in oral anticoagulant
(OAC)‐treated patients against gastrointestinal bleeding (GIB) is still lacking. We conducted …

Drug-drug interaction (DDI) is the combined effects of multiple drugs taken together, which
can either enhance or reduce each other's efficacy. Thus, drug interaction analysis plays an …

The Guidelines for the Pharmacological Treatment of Arrhythmias were first published in
2004, followed by the 2009 revision, 1 the 2013 revision of the Guidelines for the …

Background The bleeding risk of individuals taking nonsteroidal anti-inflammatory drugs
(NSAIDs) concomitantly with oral anticoagulants (OACs) compared to OACs alone remains …