The evolution of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
[HTML][HTML] SARS-CoV-2 variant biology: immune escape, transmission and fitness
AM Carabelli, TP Peacock, LG Thorne… - Nature Reviews …, 2023 - nature.com
In late 2020, after circulating for almost a year in the human population, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibited a major step change in its …
[HTML][HTML] Enhanced neutralization resistance of SARS-CoV-2 omicron subvariants BQ. 1, BQ. 1.1, BA. 4.6, BF. 7, and BA. 2.75. 2
P Qu, JP Evans, JN Faraone, YM Zheng, C Carlin… - Cell host & …, 2023 - cell.com
The continued evolution of SARS-CoV-2 has led to the emergence of several new Omicron
subvariants, including BQ. 1, BQ. 1.1, BA. 4.6, BF. 7, and BA. 2.75. 2. Here, we examine the …
subvariants, including BQ. 1, BQ. 1.1, BA. 4.6, BF. 7, and BA. 2.75. 2. Here, we examine the …
The altered entry pathway and antigenic distance of the SARS-CoV-2 Omicron variant map to separate domains of spike protein
TP Peacock, JC Brown, J Zhou, N Thakur, K Sukhova… - biorxiv, 2022 - biorxiv.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA. 1, BA. 2, and BA. 5
Summary Background Among the Omicron sublineages that have emerged, BA. 1, BA. 2,
BA. 5, and their related sublineages have resulted in the largest number of infections. While …
BA. 5, and their related sublineages have resulted in the largest number of infections. While …
Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA. 1 variant through NSP6
Abstract Although the SARS-CoV-2 Omicron variant (BA. 1) spread rapidly across the world
and effectively evaded immune responses, its viral fitness in cell and animal models was …
and effectively evaded immune responses, its viral fitness in cell and animal models was …
[HTML][HTML] Distinct neutralizing antibody escape of SARS-CoV-2 Omicron subvariants BQ. 1, BQ. 1.1, BA. 4.6, BF. 7 and BA. 2.75. 2
P Qu, JP Evans, J Faraone, YM Zheng, C Carlin… - Biorxiv, 2022 - ncbi.nlm.nih.gov
Continued evolution of SARS-CoV-2 has led to the emergence of several new Omicron
subvariants, including BQ. 1, BQ. 1.1, BA. 4.6, BF. 7 and BA. 2.75. 2. Here we examine the …
subvariants, including BQ. 1, BQ. 1.1, BA. 4.6, BF. 7 and BA. 2.75. 2. Here we examine the …
A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications
J Schön, GT Barut, BS Trüeb, NJ Halwe… - Nature …, 2024 - nature.com
Approved vaccines are effective against severe COVID-19, but broader immunity is needed
against new variants and transmission. Therefore, we developed genome-modified live …
against new variants and transmission. Therefore, we developed genome-modified live …
Omicron subvariant BA. 5 efficiently infects lung cells
Abstract The SARS-CoV-2 Omicron subvariants BA. 1 and BA. 2 exhibit reduced lung cell
infection relative to previously circulating SARS-CoV-2 variants, which may account for their …
infection relative to previously circulating SARS-CoV-2 variants, which may account for their …
Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic
SARS-CoV-2 variants are mainly defined by mutations in their spike. It is therefore critical to
understand how the evolutionary trajectories of spike affect virus phenotypes. So far, it has …
understand how the evolutionary trajectories of spike affect virus phenotypes. So far, it has …