Exploring treatment options in cancer: tumor treatment strategies

B Liu, H Zhou, L Tan, KTH Siu, XY Guan - Signal transduction and …, 2024 - nature.com
Traditional therapeutic approaches such as chemotherapy and radiation therapy have
burdened cancer patients with onerous physical and psychological challenges …

Radiotheranostics in oncology: current challenges and emerging opportunities

L Bodei, K Herrmann, H Schöder, AM Scott… - Nature Reviews …, 2022 - nature.com
Structural imaging remains an essential component of diagnosis, staging and response
assessment in patients with cancer; however, as clinicians increasingly seek to …

Advances in PET imaging of cancer

J Schwenck, D Sonanini, JM Cotton… - Nature Reviews …, 2023 - nature.com
Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

Joint EANM/SNMMI procedure guideline for the use of 177Lu-labeled PSMA-targeted radioligand-therapy (177Lu-PSMA-RLT)

C Kratochwil, WP Fendler, M Eiber, MS Hofman… - European journal of …, 2023 - Springer
Prostate-specific membrane antigen (PSMA) is expressed by the majority of clinically
significant prostate adenocarcinomas, and patients with target-positive disease can easily …

PSMA and FDG-PET as predictive and prognostic biomarkers in patients given [177Lu] Lu-PSMA-617 versus cabazitaxel for metastatic castration-resistant prostate …

JP Buteau, AJ Martin, L Emmett, A Iravani… - The Lancet …, 2022 - thelancet.com
Background Previously, results from the TheraP trial showed that treatment with lutetium-177
[177 Lu] Lu-PSMA-617 improved frequency of prostate-specific antigen (PSA) response rate …

[177Lu]Lu-PSMA-617 (PluvictoTM): The First FDA-Approved Radiotherapeutical for Treatment of Prostate Cancer

U Hennrich, M Eder - Pharmaceuticals, 2022 - mdpi.com
In March 2022,[177Lu] Lu-PSMA-617 (PluvictoTM) was approved by the FDA for the
treatment of prostate cancer patients. Until now, the approval has been limited to patients …

Neutrophil hitchhiking for drug delivery to the bone marrow

Z Luo, Y Lu, Y Shi, M Jiang, X Shan, X Li… - Nature …, 2023 - nature.com
Pharmaceuticals have been developed for the treatment of a wide range of bone diseases
and disorders, but suffer from problematic delivery to the bone marrow. Neutrophils are …

Molecular imaging in oncology: Current impact and future directions

SP Rowe, MG Pomper - CA: a cancer journal for clinicians, 2022 - Wiley Online Library
The authors define molecular imaging, according to the Society of Nuclear Medicine and
Molecular Imaging, as the visualization, characterization, and measurement of biological …

Diagnostic accuracy of 68Ga-PSMA-11 PET for pelvic nodal metastasis detection prior to radical prostatectomy and pelvic lymph node dissection: a multicenter …

TA Hope, M Eiber, WR Armstrong, R Juarez… - JAMA …, 2021 - jamanetwork.com
Importance The presence of pelvic nodal metastases at radical prostatectomy is associated
with biochemical recurrence after prostatectomy. Objective To assess the accuracy of …

Lutetium-177–PSMA-617 for metastatic castration-resistant prostate cancer

O Sartor, J De Bono, KN Chi, K Fizazi… - … England Journal of …, 2021 - Mass Medical Soc
Background Metastatic castration-resistant prostate cancer remains fatal despite recent
advances. Prostate-specific membrane antigen (PSMA) is highly expressed in metastatic …