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Polymeric delivery of therapeutic nucleic acids
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Block copolymer micelles in nanomedicine applications
Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …
controlling the distribution and function of loaded bioactive agents in the body, effectively …
Gene therapy and DNA delivery systems
Gene therapy is a promising new technique for treating many serious incurable diseases,
such as cancer and genetic disorders. The main problem limiting the application of this …
such as cancer and genetic disorders. The main problem limiting the application of this …
Block copolymer micelles for drug delivery: design, characterization and biological significance
Recently, colloidal carrier systems have been receiving much attention in the field of drug
targeting because of their high loading capacity for drugs as well as their unique disposition …
targeting because of their high loading capacity for drugs as well as their unique disposition …
Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advances
Chemotherapeutic agents have certain limitations when it comes to treating cancer, the most
important being severe side effects along with multidrug resistance developed against them …
important being severe side effects along with multidrug resistance developed against them …
Nanogels as pharmaceutical carriers: finite networks of infinite capabilities
AV Kabanov, SV Vinogradov - … Chemie International Edition, 2009 - Wiley Online Library
Nanogels are swollen nanosized networks composed of hydrophilic or amphiphilic polymer
chains. They are developed as carriers for the transport of drugs, and can be designed to …
chains. They are developed as carriers for the transport of drugs, and can be designed to …
Gene delivery by lipoplexes and polyplexes
CT de Ilarduya, Y Sun, N Düzgüneş - European journal of pharmaceutical …, 2010 - Elsevier
Gene therapy has emerged as a promising approach for the treatment or prevention of
acquired and genetic diseases. At the present time, major somatic gene transfer approaches …
acquired and genetic diseases. At the present time, major somatic gene transfer approaches …
Passive and active drug targeting: drug delivery to tumors as an example
VP Torchilin - Drug delivery, 2010 - Springer
The paradigm of using nanoparticulate pharmaceutical carriers has been well established
over the past decade, both in pharmaceutical research and in the clinical setting. Drug …
over the past decade, both in pharmaceutical research and in the clinical setting. Drug …
Poly (ethylenimine) and its role in gene delivery
Since the first published examination of poly (ethylenimine)(PEI) as a gene delivery vehicle,
there has been a flurry of research aimed at this polycation and its role in gene therapy …
there has been a flurry of research aimed at this polycation and its role in gene therapy …
Polyethylenimine-based non-viral gene delivery systems
U Lungwitz, M Breunig, T Blunk, A Göpferich - European Journal of …, 2005 - Elsevier
Gene therapy has become a promising strategy for the treatment of many inheritable or
acquired diseases that are currently considered incurable. Non-viral vectors have attracted …
acquired diseases that are currently considered incurable. Non-viral vectors have attracted …