Immune checkpoint therapy has revolutionized cancer treatment, leading to dramatic clinical
outcomes for a subset of patients. However, many patients do not experience durable …

Nanoscale metal–organic frameworks integrated with porphyrins (Por-nMOFs) have
emerged as efficient nanoplatforms for photodynamic therapy (PDT), which relies on the …

Pyroptosis, an inflammatory modality of programmed cell death associated with the immune
response, can be initiated by bioactive ions and reactive oxygen species (ROS). However …

Immunotherapy has revolutionized the cancer treatment paradigm, yet efficient
immunotherapeutic responses against immune-cold/desert cancers remain challenging …

Immune checkpoint inhibitors (ICIs) have dramatically transformed the treatment landscape
for various malignancies, achieving notable clinical outcomes across a wide range of …

Cancer vaccines have garnered attention as a potential treatment for cancer metastases.
Nevertheless, the clinical response rate to vaccines remains< 30%. Nanoparticles stabilize …

As one of the important members of the family of chemokines and their receptors, the
CXCL13/CXCR5 axis is involved in follicle formation in normal lymphoid tissues and the …

Cancer immunotherapy, as an emerging cancer treatment approach, harnesses the patient's
own immune system to effectively prevent tumor recurrence or metastasis. However, its …

Identifying definitive biomarkers that predict clinical response and resistance to
immunotherapy remains a critical challenge. One emerging factor is extracellular acidosis in …

Accurately evaluating tumor neoangiogenesis and conducting precise interventions toward
an immune‐favorable microenvironment are of significant clinical importance. In this study, a …