X-ray computed tomography (CT) can reveal the internal details of objects in three
dimensions non-destructively. In this Primer, we outline the basic principles of CT and …

Zebrafish are teleosts (bony fish) that share with mammals a common ancestor belonging to
the phylum Osteichthyes, from which their endoskeletal systems have been inherited …

Dense reconstruction of synaptic connectivity requires high-resolution electron microscopy
images of entire brains and tools to efficiently trace neuronal wires across the volume. To …

Modern biomedical research and preclinical pharmaceutical development rely heavily on
the phenoty** of small vertebrate models for various diseases prior to human testing. In …

The decreasing cost of acquiring computed tomographic (CT) data has fueled a global effort
to digitize the anatomy of museum specimens. This effort has produced a wealth of open …

Advances in next‐generation sequencing have transformed our ability to identify genetic
variants associated with clinical disorders of the musculoskeletal system. However, the …

We present a three-dimensional (3D) approach for virtual histology and histopathology
based on multi-scale phase contrast x-ray tomography, and use this to investigate the …

A multiscale three-dimensional (3D) virtual histology approach is presented, based on two
configurations of propagation phase-contrast X-ray tomography, which have been …

Zebrafish has become an essential model organism in modern biomedical research. Owing
to its distinctive features and high grade of genomic homology with humans, it is increasingly …

Photoacoustic tomography (PAT) is a rapidly emerging biomedical imaging modality. To
achieve high-performance imaging, signal acquisition in PAT should ideally meet conditions …