Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y ** model was developed to assess the
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19
C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in Molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …
GABAA receptors as targets for anaesthetics and analgesics and promising candidates to help treat coronavirus infections: A mini‐review
Y Luo, T Balle - Basic & Clinical Pharmacology & Toxicology, 2022 - Wiley Online Library
GABA is a major inhibitory neurotransmitter that regulates the balance between excitatory
and inhibitory circuits in the human nervous system. The GABA receptors are divided into …
and inhibitory circuits in the human nervous system. The GABA receptors are divided into …
Metabolic pathway analysis: advantages and pitfalls for the functional interpretation of metabolomics and lipidomics data
S Tsouka, M Masoodi - Biomolecules, 2023 - mdpi.com
Over the past decades, pathway analysis has become one of the most commonly used
approaches for the functional interpretation of metabolomics data. Although the approach is …
approaches for the functional interpretation of metabolomics data. Although the approach is …
Severe COVID-19 is characterised by perturbations in plasma amines correlated with immune response markers, and linked to inflammation and oxidative stress
The COVID-19 pandemic raised a need to characterise the biochemical response to SARS-
CoV-2 infection and find biological markers to identify therapeutic targets. In support of these …
CoV-2 infection and find biological markers to identify therapeutic targets. In support of these …
Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID
AS Naidu, CK Wang, P Rao, F Mancini… - npj Science of …, 2024 - nature.com
Abstract SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …
Untangling the link between the human gut microbiota composition and the severity of the symptoms of the COVID‐19 infection
L Mancabelli, C Milani, F Fontana… - Environmental …, 2022 - Wiley Online Library
Recent pandemic infection caused by SARS‐CoV‐2 (COVID‐19) led the scientific
community to investigate the possible causes contributing to the physiopathology of this …
community to investigate the possible causes contributing to the physiopathology of this …