Kick-starting the zygotic genome: licensors, specifiers, and beyond
Zygotic genome activation (ZGA), the first transcription event following fertilization, kickstarts
the embryonic program that takes over the control of early development from the maternal …
the embryonic program that takes over the control of early development from the maternal …
[HTML][HTML] Genome folding and zygotic genome activation in mammalian preimplantation embryos
A Bondarieva, K Tachibana - Current Opinion in Genetics & Development, 2024 - Elsevier
The totipotent one-cell embryo, or zygote, gives rise to all germ layers and extraembryonic
tissues that culminate in the development of a new organism. A zygote is produced at …
tissues that culminate in the development of a new organism. A zygote is produced at …
Comparative study of the three-dimensional genomes of granulosa cells in germinal vesicle and metaphase II follicles
R Mao, Z Cai, T Wang, Y Li, S Tian, D Li, P Li - Frontiers in Genetics, 2024 - frontiersin.org
Introduction Follicle development is a critical process in the female reproductive system, with
significant implications for fertility and reproductive health. Germinal vesicle (GV) oocytes …
significant implications for fertility and reproductive health. Germinal vesicle (GV) oocytes …
H3K4me2 distinguishes a distinct class of enhancers during the maternal-to-zygotic transition
MD Hurton, JM Miller, MT Lee - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
After egg fertilization, an initially silent embryonic genome is transcriptionally activated
during the maternal-to-zygotic transition. In zebrafish, maternal vertebrate pluripotency …
during the maternal-to-zygotic transition. In zebrafish, maternal vertebrate pluripotency …
[CITATION][C] Cellular and molecular regulations of oocyte selection and activation in mammals
X Yang, Y Zhang, H Zhang - 2024 - Elsevier