Erectile dysfunction: treatments, advances and new therapeutic strategies

A Argiolas, FM Argiolas, G Argiolas, MR Melis - Brain sciences, 2023‏ - mdpi.com
Erectile dysfunction (ED) is the inability to get and maintain an adequate penile erection for
satisfactory sexual intercourse. Due to its negative impacts on men's life quality and increase …

Antibacterial activity of medicinal plants and their role in wound healing

Z Breijyeh, R Karaman - Future Journal of Pharmaceutical Sciences, 2024‏ - Springer
Background The study of plant-based medications, or phytomedicine, involves a wide
spectrum of biological activities. Due to the existence of secondary metabolites, herbal …

Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency

J Scekic-Zahirovic, C Benetton, A Brunet… - Science Translational …, 2024‏ - science.org
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease,
characterized by the death of upper (UMN) and lower motor neurons (LMN) in the motor …

A revised conceptual framework for mouse vomeronasal pum** and stimulus sampling

C Hamacher, R Degen, M Franke, VK Switacz, D Fleck… - Current Biology, 2024‏ - cell.com
The physiological performance of any sensory organ is determined by its anatomy and
physical properties. Consequently, complex sensory structures with elaborate features have …

Effects of nutrition interventions on athletic performance in soccer players: a systematic review

I Aguinaga-Ontoso, S Guillen-Aguinaga… - Life, 2023‏ - mdpi.com
Background: More than 270 million participants and 128,893 professional players play
soccer. Although UEFA recommendations for nutrition in elite football exist, implementing …

Structural insight into groove binding of yohimbine with calf thymus DNA: A spectroscopic, calorimetric, and computational approach

S Luikham, A Mavani, D Sinha… - The Journal of Physical …, 2023‏ - ACS Publications
A variety of anticancer and antibacterial drugs target DNA as one of their primary
intracellular targets. Understanding ligand–DNA interactions and develo** new …

[PDF][PDF] The new stealth drug on the street: a narrative review of xylazine as a street drug

J Pergolizzi Jr, JAK LeQuang, P Magnusson, TL Miller… - Cureus, 2023‏ - cureus.com
Xylazine is an alpha-adrenergic receptor agonist approved for use only in animals with a
prescription from a veterinarian. It is a powerful sedative that is slowly infiltrating the …

Phenolic acids-mediated regulation of molecular targets in ovarian cancer: Current understanding and future perspectives

N Nazam, NR Jabir, I Ahmad, SA Alharthy, MS Khan… - Pharmaceuticals, 2023‏ - mdpi.com
Cancer is a global health concern with a dynamic rise in occurrence and one of the leading
causes of mortality worldwide. Among different types of cancer, ovarian cancer (OC) is the …

Investigating the crosstalk between chronic stress and immune cells: implications for enhanced cancer therapy

YR Lei, F Liao, YC Tian, YN Wang, F **a… - Frontiers in …, 2023‏ - frontiersin.org
Chronic stress has a substantial influence on the tumor microenvironment (TME), leading to
compromised effectiveness of anti-cancer therapies through diverse mechanisms. It disrupts …

Anticancer effect of antioxidant-rich methanolic extract of Rauvolfia serpentina (L.) Benth. ex Kurz leaves in HepG2 and HeLa cells: A mechanistic insight

AC Roy, A Prasad, K Priya, P Das, S Singh… - Biocatalysis and …, 2023‏ - Elsevier
Abstract Rauvolfia serpentina (L.) Benth. ex Kurz is a pharmaceutically, and agriculturally
important medicinal plant traditionally used against snake and insect bites, dysentery …