Flavonoids, terpenoids, and polyketide antibiotics: Role of glycosylation and biocatalytic tactics in engineering glycosylation
Flavonoids, terpenoids, and polyketides are structurally diverse secondary metabolites used
widely as pharmaceuticals and nutraceuticals. Most of these molecules exist in nature as …
widely as pharmaceuticals and nutraceuticals. Most of these molecules exist in nature as …
Engineered production of bioactive polyphenolic O-glycosides
Polyphenolic compounds (such as quercetin and resveratrol) possess potential medicinal
values due to their various bioactivities, but poor water solubility hinders their health benefits …
values due to their various bioactivities, but poor water solubility hinders their health benefits …
Recent advances in the metabolic engineering of yeasts for ginsenoside biosynthesis
Ginsenosides are a group of glycosylated triterpenes isolated from Panax species.
Ginsenosides are promising candidates for the prevention and treatment of cancer as well …
Ginsenosides are promising candidates for the prevention and treatment of cancer as well …
Tailored functionalization of natural phenols to improve biological activity
Phenols are widespread in nature, being the major components of several plants and
essential oils. Natural phenols' anti-microbial, anti-bacterial, anti-oxidant, pharmacological …
essential oils. Natural phenols' anti-microbial, anti-bacterial, anti-oxidant, pharmacological …
Advances in biochemistry and the biotechnological production of taxifolin and its derivatives
Taxifolin (dihydroquercetin) and its derivatives are medicinally important flavanonols with a
wide distribution in plants. These compounds have been isolated from various plants, such …
wide distribution in plants. These compounds have been isolated from various plants, such …
Chemical and molecular characterization of metabolites from Flavobacterium sp.
In this study, a Flavobacterium sp. is isolated from natural spring, and identified using
molecular techniques. Extracellular and intracellular secondary metabolites are identified …
molecular techniques. Extracellular and intracellular secondary metabolites are identified …
Escherichia coli modular coculture system for resveratrol glucosides production
In bio-based fermentation, the overall bioprocess efficiency is significantly affected by the
metabolic burden associated with the expression of complete biosynthetic pathway as well …
metabolic burden associated with the expression of complete biosynthetic pathway as well …
Constitutive Polyphenols in Blades and Veins of Grapevine (Vitis vinifera L.) Healthy Leaves
O Kedrina-Okutan, V Novello, T Hoffmann… - Journal of agricultural …, 2018 - ACS Publications
Despite the economic importance and the diffusion of grapevine cultivation worldwide, little
is known about leaf chemical composition. We characterized the phenolic composition of …
is known about leaf chemical composition. We characterized the phenolic composition of …
[HTML][HTML] High level production of flavonoid rhamnosides by metagenome-derived glycosyltransferase C in Escherichia coli utilizing dextrins of starch as a single …
C Ruprecht, F Bönisch, N Ilmberger, TV Heyer… - Metabolic …, 2019 - Elsevier
Flavonoids exert a wide variety of biological functions that are highly attractive for the
pharmaceutical and healthcare industries. However, their application is often limited by low …
pharmaceutical and healthcare industries. However, their application is often limited by low …
Improved production of 1-deoxynojirymicin in Escherichia coli through metabolic engineering
Abstract Azasugars, such as 1-deoxynojirymicin (1-DNJ), are associated with diverse
pharmaceutical applications, such as antidiabetic, anti-obesity, anti-HIV, and antitumor …
pharmaceutical applications, such as antidiabetic, anti-obesity, anti-HIV, and antitumor …