Commentary: Two-sample Mendelian randomization: opportunities and challenges
DA Lawlor - International journal of epidemiology, 2016 - academic.oup.com
In this volume of the IJE, Gao and colleagues explore the causal effect of adiposity on
several cancers using twosample Mendelian randomization (MR), and find some evidence …
several cancers using twosample Mendelian randomization (MR), and find some evidence …
Triangulation in aetiological epidemiology
DA Lawlor, K Tilling… - International journal of …, 2016 - academic.oup.com
Triangulation is the practice of obtaining more reliable answers to research questions
through integrating results from several different approaches, where each approach has …
through integrating results from several different approaches, where each approach has …
Sensitive periods for the effect of childhood adversity on DNA methylation: results from a prospective, longitudinal study
Background Exposure to early-life adversity is known to predict DNA methylation (DNAm)
patterns that may be related to psychiatric risk. However, few studies have investigated …
patterns that may be related to psychiatric risk. However, few studies have investigated …
Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children
Objectives Exposure to adversity has been linked to accelerated biological aging, which in
turn has been shown to predict numerous physical and mental health problems. In recent …
turn has been shown to predict numerous physical and mental health problems. In recent …
What life course theoretical models best explain the relationship between exposure to childhood adversity and psychopathology symptoms: recency, accumulation, or …
BackgroundAlthough childhood adversity is a potent determinant of psychopathology,
relatively little is known about how the characteristics of adversity exposure, including its …
relatively little is known about how the characteristics of adversity exposure, including its …
The last two decades of life course epidemiology, and its relevance for research on ageing
The term 'life course epidemiology'was coined in 1997 with the publication of the first edition
of A Life Course Approach to Chronic Disease Epidemiology. 1 This book reviewed the pre …
of A Life Course Approach to Chronic Disease Epidemiology. 1 This book reviewed the pre …
Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of …
Background Childhood adversity is a potent determinant of health across development and
is associated with altered DNA methylation signatures, which might be more common in …
is associated with altered DNA methylation signatures, which might be more common in …
[HTML][HTML] Life-course exposure to air pollution and biological ageing in the Lothian Birth Cohort 1936
Background Exposure to air pollution is associated with a range of diseases. Biomarkers
derived from DNA methylation (DNAm) offer potential mechanistic insights into human …
derived from DNA methylation (DNAm) offer potential mechanistic insights into human …
An integrative approach for the analysis of risk and health across the life course: challenges, innovations, and opportunities for life course research
Life course epidemiology seeks to understand the intricate relationships between risk factors
and health outcomes across different stages of life to inform prevention and intervention …
and health outcomes across different stages of life to inform prevention and intervention …
Life-course influences of poverty on violence and homicide: 30-year Brazilian birth cohort study
J Murray, M Degli Esposti… - International journal …, 2024 - academic.oup.com
Background Homicide is the leading cause of death among young people in Latin America,
one of the world's most violent regions. Poverty is widely considered a key cause of …
one of the world's most violent regions. Poverty is widely considered a key cause of …