[HTML][HTML] Strategies to improve bioactive and antibacterial properties of polyetheretherketone (PEEK) for use as orthopedic implants

Z Zheng, P Liu, X Zhang, X Zou, X Mei, S Zhang… - Materials Today Bio, 2022 - Elsevier
Polyetheretherketone (PEEK) has gradually become the mainstream material for preparing
orthopedic implants due to its similar elastic modulus to human bone, high strength …

Modification of polyetheretherketone implants: From enhancing bone integration to enabling multi-modal therapeutics

M He, Y Huang, H Xu, G Feng, L Liu, Y Li, D Sun… - Acta biomaterialia, 2021 - Elsevier
Polyetheretherketone (PEEK) is a popular thermoplastic material widely used in engineering
applications due to its favorable mechanical properties and stability at high temperatures …

MXene-based hydrogels endow polyetheretherketone with effective osteogenicity and combined treatment of osteosarcoma and bacterial infection

J Yin, Q Han, J Zhang, Y Liu, X Gan, K **e… - … Applied Materials & …, 2020 - ACS Publications
After an osteosarcoma resection, the risks of cancer recurrence, postoperative infection, and
large bone loss still threaten patients' health. Conventional treatment relies on implanting …

Surface engineering of biomaterials in orthopedic and dental implants: Strategies to improve osteointegration, bacteriostatic and bactericidal activities

Z Liu, X Liu, S Ramakrishna - Biotechnology journal, 2021 - Wiley Online Library
Background The success of biomedical implants in orthopedic and dental applications is
usually limited due to insufficient bone‐implant integration, and implant‐related infections …

Surface treatments of PEEK for osseointegration to bone

JR Dondani, J Iyer, SD Tran - Biomolecules, 2023 - mdpi.com
Polymers, in general, and Poly (Ether-Ether-Ketone)(PEEK) have emerged as potential
alternatives to conventional osseous implant biomaterials. Due to its distinct advantages …

[HTML][HTML] A dual-functional PEEK implant coating for anti-bacterial and accelerated osseointegration

X Yang, Q Wang, Y Zhang, H He, S **ong… - Colloids and Surfaces B …, 2023 - Elsevier
Polyetheretherketone (PEEK) has been widely applied in biomedical engineering. However,
the unsatisfactory bioactivity essentially limits the clinical application of PEEK. In this study, a …

Strategies to improve the performance of polyetheretherketone (PEEK) as orthopedic implants: from surface modification to addition of bioactive materials

H Huang, X Liu, J Wang, M Suo, J Zhang… - Journal of Materials …, 2024 - pubs.rsc.org
Polyetheretherketone (PEEK), as a high-performance polymer, is widely used for bone
defect repair due to its homogeneous modulus of elasticity of human bone, good …

Porous surface with fusion peptides embedded in strontium titanate nanotubes elevates osteogenic and antibacterial activity of additively manufactured titanium alloy

B Wang, J Lan, H Qiao, L **e, H Yang, H Lin… - Colloids and Surfaces B …, 2023 - Elsevier
It is still a big challenge in orthopedics to treat infected bone defects properly using medical
metals. The use of three-dimensional (3D) scaffold materials that simultaneously mimic the …

The application of polyetheretherketone (PEEK) implants in cranioplasty

J Zhang, W Tian, J Chen, J Yu, J Zhang, J Chen - Brain research bulletin, 2019 - Elsevier
Cranioplasty is a challenge to neurosurgeons, especially considering protection of
intracranial contents. In recent years, material choice for cranioplasty is still controversial …

Application of biomolecules modification strategies on PEEK and its composites for osteogenesis and antibacterial properties

X Han, W Gao, Z Zhou, S Yang, J Wang, R Shi… - Colloids and Surfaces B …, 2022 - Elsevier
As orthopedic and dental implants, polyetheretherketone (PEEK) is expected to be a
common substitute material of titanium (Ti) and its alloys due to its good biocompatibility …