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Pursuing effective vaccines against cattle diseases caused by apicomplexan protozoa
Apicomplexan parasites are responsible for important livestock diseases that affect the
production of much needed protein resources, and those transmissible to humans pose a …
production of much needed protein resources, and those transmissible to humans pose a …
[HTML][HTML] Neosporosis: an overview of its molecular epidemiology and pathogenesis
Abstract Neospora caninum (N. caninum), a cyst-forming protozoan parasite, is a major
cause of bovine abortions and neonatal mortality worldwide. N. caninum has a broad …
cause of bovine abortions and neonatal mortality worldwide. N. caninum has a broad …
Neospora caninum dense granule protein 7 regulates the pathogenesis of neosporosis by modulating host immune response
Neospora caninum is a protozoan parasite closely related to Toxoplasma gondii.
Neosporosis caused by N. caninum is considered one of the main causes of abortion in …
Neosporosis caused by N. caninum is considered one of the main causes of abortion in …
[HTML][HTML] NcGRA7 and NcROP40 Play a Role in the Virulence of Neospora caninum in a Pregnant Mouse Model
L Rico-San Román, R Amieva, J Regidor-Cerrillo… - Pathogens, 2022 - mdpi.com
The intraspecific variability among Neospora caninum isolates in their in vitro behaviour and
in vivo virulence has been widely studied. In particular, transcriptomic and proteomic …
in vivo virulence has been widely studied. In particular, transcriptomic and proteomic …
Combination therapy against multidrug resistance
M Marimani - Combination Therapy Against Multidrug Resistance, 2020 - Elsevier
Many microbial pathogens have developed different strategies that enable them to survive
and flourish in the presence of antimicrobial agents that would otherwise kill or inhibit their …
and flourish in the presence of antimicrobial agents that would otherwise kill or inhibit their …
[HTML][HTML] Characterization of Neospora caninum virulence factors NcGRA7 and NcROP40 in bovine target cells
L Rico-San Román, R Amieva, P Horcajo… - Veterinary …, 2023 - Elsevier
Bovine neosporosis is one of the major causes of reproductive failure in cattle worldwide,
and differences in virulence between isolates have been widely shown. However, the …
and differences in virulence between isolates have been widely shown. However, the …
Genetic manipulation toolkits in apicomplexan parasites
Z Niu, L Xue, X Yin, B Shen - Zoonoses, 2022 - scienceopen.com
Apicomplexan parasites are a group of intracellular pathogens of great medical and
veterinary importance, including Toxoplasma gondii and Plasmodium, which cause …
veterinary importance, including Toxoplasma gondii and Plasmodium, which cause …
Are genetically modified protozoa eligible for ATMP status? Concerning the legal categorization of an oncolytic protozoan drug candidate
M Guerriaud, C Poupet, Z Lakhrif, E Kohli, N Moiré - Gene Therapy, 2024 - nature.com
Neospora caninum is an obligate intracellular protozoan that affects several animal species.
It is not pathogenic for humans, and its ability to infect and lyse a variety of cells and …
It is not pathogenic for humans, and its ability to infect and lyse a variety of cells and …
Efficient gene knockout and knockdown systems in Neospora caninum enable rapid discovery and functional assessment of novel proteins
The development of molecular genetics has greatly enhanced the study of the biology and
pathology associated with parasites of the phylum Apicomplexa. While the molecular tools …
pathology associated with parasites of the phylum Apicomplexa. While the molecular tools …
Genome editing in apicomplexan parasites: Current status, challenges, and future possibilities
Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated
protein (Cas) technology has revolutionized genome editing across various biological …
protein (Cas) technology has revolutionized genome editing across various biological …