During sepsis, a complex network of cytokine, immune, and endothelial cell interactions
occur and disturbances in the microcirculation cause organ dysfunction or even failure …

OBJECTIVES The objectives of this review were to critically assess and summarize trauma
outcome disparities by race, insurance, and SES and to determine if racial disparities are …

Background Sex differences are important epidemiological factors that impact in the
frequency and severity of infectious diseases. A clear sexual dimorphism in bacterial …

Abstract Background In 1999, an Utstein Template for Uniform Reporting of Data following
Major Trauma was published. Few papers have since been published based on that …

Objective: To characterize the epidemiology of sepsis in trauma. Design: Analysis of a
prospectively collected administrative database (Pennsylvania trauma registry). Setting: All …

BACKGROUND: Obesity has risen at an epidemic rate over the past 20 years in the US. To
our knowledge, there is an absence of data evaluating the impact of obesity in the critically ill …

Nosocomial pneumonia in trauma patients is a significant source of resource utilization and
mortality. We have previously described increased rates of pneumonia in male trauma …

Abstract Hemorrhage, trauma, ischemia/reperfusion, burn, and sepsis each lead to cardiac
dysfunction. These insults lead to an inflammatory cascade, which plays an important role in …

Background: Pre-existing medical conditions (PMCs) have been shown to increase mortality
after trauma even after adjustment for the effect of chronological aging. It has been …

Background Several studies have reported a null association between gender and mortality
after traumatic injury, whereas others found an age-specific association between male …