Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Background IL-10 has anti-inflammatory and CD8+ T-cell stimulating activities.
Pegilodecakin (pegylated IL-10) is a first-in-class, long-acting IL-10 receptor agonist that …

Objectives COVID-19 is a transmissible illness triggered by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). Since its onset in late 2019 in Wuhan city of China …

Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease that can lead to
hepatocyte destruction, inflammation, liver fibrosis, cirrhosis, and liver failure. The diagnosis …

Background Pro-and anti-inflammatory cytokines are important mediators of immunity and
are associated with malaria disease outcomes. However, their role in the establishment of …

Abstract CD4 T-helper (Th) cells secret a variety of inflammatory cytokines and play critical
roles in host defense against invading foreign pathogens. On the other hand, uncontrolled …

Despite extensive map** of long noncoding RNAs in immune cells, their function in vivo
remains poorly understood. In this study, we identify over 100 long noncoding RNAs that are …

Behçet's syndrome (BS) is a systemic vasculitis with several clinical manifestations.
Neutrophil hyperactivation mediates vascular BS pathogenesis, via both a massive reactive …

Malaria, caused by Plasmodium species, remains a major global health concern, causing
millions of deaths annually. While the introduction of the RTS, S vaccine has shown promise …