Alcohol use disorder (AUD) is a widespread disease with limited treatment options.
Targeting the neuroimmune system is a new avenue for develo** or repurposing effective …

Abstract Purpose of Review Suicide is a major public health concern and a leading cause of
death in the US. Alcohol and opioid use disorders (AUD/OUD) significantly increase risk for …

We summarise the evidence for medicinal uses of opioids, harms related to the extramedical
use of, and dependence on, these drugs, and a wide range of interventions used to address …

Importance The use of benzodiazepines or alcohol together with opioids increases
overdose risk, but characterization of co-involvement by predominant opioid subtype is …

Population Comprehensive evaluation of chronic pain in older adults is multifaceted.
Objective and Methods Research on chronic pain in older adults needs to be guided by …

Importance An increase in opioid prescription has been observed in the Netherlands. It is
vital to understand this increase and to identify risk factors for opioid prescription to ensure …

Nutrition plays an important role in pain management. Healthy eating patterns are
associated with reduced systemic inflammation, as well as lower risk and severity of chronic …

Background Chronic non-cancer pain (CNCP) among patients with substance use disorder
(SUD) poses a risk for worse treatment outcomes. Understanding the association of CNCP …

Background A mounting body of evidence suggests that polysubstance use (PSU) is
common among people who use opioids (PWUO). Measuring PSU, however, is statistically …

Accumulating evidence indicates pain may be an important risk factor for development of
alcohol use disorder (AUD) and risk of relapse for people recovering from AUD. This study …