Ferroptosis, a form of cell death driven by iron-dependent lipid peroxidation, was identified
as a distinct phenomenon and named a decade ago. Ferroptosis has been implicated in a …

Ferroptosis, a newly emerged form of regulated necrotic cell death, has been demonstrated
to play an important role in multiple diseases including cancer, neurodegeneration, and …

The research field of ferroptosis has seen exponential growth over the past few years, since
the term was coined in 2012. This unique modality of cell death, driven by iron-dependent …

Cell death can be executed through different subroutines. Since the description of
ferroptosis as an iron-dependent form of non-apoptotic cell death in 2012, there has been …

Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death driven by
excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of …

Ferroptosis is widely involved in degenerative diseases in various tissues including kidney,
liver and brain, and is a targetable vulnerability in multiple primary and therapy-resistant …

Ferroptosis is a non-apoptotic form of cell death characterized by iron-dependent lipid
peroxidation and metabolic constraints. Dependence on NADPH/H+, polyunsaturated fatty …

Oxygen is necessary for aerobic metabolism but can cause the harmful oxidation of lipids
and other macromolecules. Oxidation of cholesterol and phospholipids containing …

The term ferroptosis was coined in 2012 to describe an iron-dependent regulated form of
cell death caused by the accumulation of lipid-based reactive oxygen species; this type of …

Ferroptosis, a non-apoptotic form of programmed cell death, is triggered by oxidative stress
in cancer, heat stress in plants, and hemorrhagic stroke. A homeostatic transcriptional …