Diffusion MRI (dMRI) has proven to be a useful imaging approach for both clinical diagnosis
and research investigating the microstructures of nervous tissues, and it has helped us to …

Myelin is critical for healthy brain function. An accurate in vivo measure of myelin content
has important implications for understanding brain plasticity and neurodegenerative …

Magnetic resonance is an exceptionally powerful and versatile measurement technique. The
basic structure of a magnetic resonance experiment has remained largely unchanged for …

Several MRI measures have been proposed as in vivo biomarkers of myelin, each with
applications ranging from plasticity to pathology. Despite the availability of these myelin …

Abstract T1, T2, and magnetization transfer (MT) measurements were performed in vitro at 3
T and 37° C on a variety of tissues: mouse liver, muscle, and heart; rat spinal cord and …

The image contrast in magnetic resonance imaging (MRI) is highly sensitive to several
mechanisms that are modulated by the properties of the tissue environment. The degree and …

Myelination, the elaboration of myelin surrounding neuronal axons, is essential for normal
brain function. The development of the myelin sheath enables rapid synchronized …

Several quantitative magnetic resonance (MR) measures are used to investigate multiple
sclerosis (MS) in vivo. Precise quantitative investigation of the histopathological correlates of …

Various magnetic resonance (MR) techniques are used to study the pathological evolution
of demyelinating diseases, such as multiple sclerosis (MS). However, few studies have …

Age-related microstructural differences have been detected using diffusion tensor imaging
(DTI). Although DTI is sensitive to the effects of aging, it is not specific to any underlying …