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The use of computational fluid dynamics in the development of ventricular assist devices
Progress in the field of prosthetic cardiovascular devices has significantly contributed to the
rapid advancements in cardiac therapy during the last four decades. The concept of …
rapid advancements in cardiac therapy during the last four decades. The concept of …
[HTML][HTML] Occlusive thrombosis in arteries
Thrombus formation in major arteries is life threatening. In this review article, we discuss
how an arterial thrombus can form under pathologically high shear stresses, with bonding …
how an arterial thrombus can form under pathologically high shear stresses, with bonding …
A quantitative comparison of mechanical blood damage parameters in rotary ventricular assist devices: shear stress, exposure time and hemolysis index
Ventricular assist devices (VADs) have already helped many patients with heart failure but
have the potential to assist more patients if current problems with blood damage (hemolysis …
have the potential to assist more patients if current problems with blood damage (hemolysis …
Acquired von Willebrand syndrome in patients with extracorporeal life support (ECLS)
C Heilmann, U Geisen, F Beyersdorf, L Nakamura… - Intensive care …, 2012 - Springer
Purpose Extracorporeal life support (ECLS) is used for patients with refractory heart failure
with or without respiratory failure. This temporary support is provided by blood pumps which …
with or without respiratory failure. This temporary support is provided by blood pumps which …
An extended pattern search approach to wind farm layout optimization
BL Du Pont, J Cagan - 2012 - asmedigitalcollection.asme.org
An extended pattern search approach is presented for the optimization of the placement of
wind turbines on a wind farm. Problem-specific extensions infuse stochastic characteristics …
wind turbines on a wind farm. Problem-specific extensions infuse stochastic characteristics …
Flow features and device‐induced blood trauma in CF‐VADs under a pulsatile blood flow condition: a CFD comparative study
In this study, the flow features and device‐associated blood trauma in 4 clinical ventricular
assist devices (VADs; 2 implantable axial VADs, 1 implantable centrifugal VAD, and 1 …
assist devices (VADs; 2 implantable axial VADs, 1 implantable centrifugal VAD, and 1 …
Quantification of shear‐induced platelet activation: high shear stresses for short exposure time
Thrombosis and thromboembolism are the life‐threatening clinical complications for patients
supported or treated with prosthetic cardiovascular devices. The high mechanical shear …
supported or treated with prosthetic cardiovascular devices. The high mechanical shear …
Comparison of two platelet activation markers using flow cytometry after in vitro shear stress exposure of whole human blood
Q Lu, RA Malinauskas - Artificial organs, 2011 - Wiley Online Library
Platelet activation is the initiating step to thromboembolic complications in blood‐contacting
medical devices. Currently, there are no widely accepted testing protocols or relevant …
medical devices. Currently, there are no widely accepted testing protocols or relevant …
Analysis of rotary ventricular assist devices using CFD technique—a review
With the increasing focus on reducing deaths because of heart ailments, considerable
emphasis has been directed toward the development of ventricular assist devices (VADs) …
emphasis has been directed toward the development of ventricular assist devices (VADs) …
Distribution and history of extensional stresses on vWF surrogate molecules in turbulent flow
The configuration of proteins is critical for their biochemical behavior. Mechanical stresses
that act on them can affect their behavior leading to the development of decease. The von …
that act on them can affect their behavior leading to the development of decease. The von …