Side effects of methotrexate therapy for rheumatoid arthritis: A systematic review

W Wang, H Zhou, L Liu - European journal of medicinal chemistry, 2018 - Elsevier
Methotrexate (MTX) is used as an anchor disease-modifying anti-rheumatic drugs
(DMARDs) in treating rheumatoid arthritis (RA) because of its potent efficacy and tolerability …

[HTML][HTML] Methotrexate mechanism in treatment of rheumatoid arthritis

B Friedman, B Cronstein - Joint bone spine, 2019 - Elsevier
Methotrexate has been used in treatment of rheumatoid arthritis (RA) since the 1980s and to
this day is often the first line medication for RA treatment. In this review, we examine multiple …

EuroGuiDerm Guideline on the systemic treatment of Psoriasis vulgaris–Part 1: treatment and monitoring recommendations

A Nast, C Smith, PI Spuls, G Avila Valle… - Journal of the …, 2020 - Wiley Online Library
This evidence‐and consensus‐based guideline on the treatment of psoriasis vulgaris was
developed following the EuroGuiDerm Guideline and Consensus Statement Development …

[HTML][HTML] Current therapeutic options in the treatment of rheumatoid arthritis

BM Köhler, J Günther, D Kaudewitz… - Journal of clinical …, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic
inflammation of the joints. Untreated RA leads to a destruction of joints through the erosion …

Adverse effects of low-dose methotrexate: a randomized trial

DH Solomon, RJ Glynn, EW Karlson, F Lu… - Annals of internal …, 2020 - acpjournals.org
Background: Low-dose methotrexate (LD-MTX) is the most commonly used drug for
systemic rheumatic diseases worldwide and is the recommended first-line agent for …

Excluding non-English publications from evidence-syntheses did not change conclusions: a meta-epidemiological study

B Nussbaumer-Streit, I Klerings, AI Dobrescu… - Journal of clinical …, 2020 - Elsevier
Objectives We aimed to assess whether limiting the inclusion criteria solely to English-
language publications affected the overall conclusions of evidence syntheses. Study Design …

Metabolic control of autoimmunity and tissue inflammation in rheumatoid arthritis

J Qiu, B Wu, SB Goodman, GJ Berry… - Frontiers in …, 2021 - frontiersin.org
Like other autoimmune diseases, rheumatoid arthritis (RA) develops in distinct stages, with
each phase of disease linked to immune cell dysfunction. HLA class II genes confer the …

Development and characterisation of novel poly (vinyl alcohol)/poly (vinyl pyrrolidone)-based hydrogel-forming microneedle arrays for enhanced and sustained …

IA Tekko, G Chen, J Domínguez-Robles… - International journal of …, 2020 - Elsevier
Methotrexate (MTX) is one of the mainstays of treatment for rheumatoid arthritis (RA) and
juvenile idiopathic arthritis (JIA) and it is mainly administered either orally or by …

Homocysteine induces oxidative stress and ferroptosis of nucleus pulposus via enhancing methylation of GPX4

X Zhang, Z Huang, Z **e, Y Chen, Z Zheng… - Free Radical Biology …, 2020 - Elsevier
Homocysteine (Hcy) is an amino acid involved in gene methylation. Plasma concentration of
Hcy is elevated in the pathological condition hyperhomocysteinemia (HHcy), which …

Nutrition in pediatric inflammatory bowel disease: a position paper on behalf of the Porto Inflammatory Bowel Disease Group of the European Society of Pediatric …

E Miele, R Shamir, M Aloi, A Assa… - Journal of pediatric …, 2018 - journals.lww.com
Methods: A group of 20 experts in pediatric IBD participated in an iterative consensus
process including 2 face-to-face meetings, following an open call to Nutrition Committee of …